Cancer is most accurately described as a class of diseases characterized by uncontrolled cell growth and division.There are more than a hundred defined types of cancer.

Cancer can occur in nearly every organ or tissue in the body.

Various small molecules are widely used in the research of cancer. Especially in the last decade, cancer research has evolved from a one-size-fits-all approach that emphasized cytotoxic chemotherapy to a more personalized medical strategy that focuses on the discovery and development of targeted drugs.

These drugs are designed, on a molecular level, to exploit particular genetic dependencies, addictions, and vulnerabilities of cancer cells.

Much current cancer research is concentrated in the areas of programmed cell death, tumor invasion and angiogenesis, tumor immunology, oncogenic signaling, gene expression and copy number, epigenetic regulation, toxicity and chemoresistance, metabolic stress and damage to DNA. Fermentek offers more than 30 unique biochemicals currently being used in cancer research.

Ansamitocin P3

Ansamitocin P3
Molecular Formula
C32H43ClN2O9
M.W.
635.14
CAS number
66584-72-3
MSDS
Source
Actinosynnema pretoisum
Fermentek product Code
ANS-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Names and synonyms

  • Maytansinol ISO-butyrate
  • Antibiotic C15003P3
  • Ansamitocin P-3
  • Ansamitocin P3

RTECS: OQ2291000

EU number
680-663-6
Chemical name
Maytansinol isobutyrate
Description

Fungal metabolite with antimitotic, antineoplastic activity. Ansamitocin P3 binds to tubulin and inhibits vinblastine-induced spiral formation

InChl Key
OPQNCARIZFLNLF-JBHFWYGFSA-N
Canonical SMILES
CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)C)C)C)OC)(NC(=O)O2)O
Isomeric SMILES
C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)C(C)C)C)\C)OC)(NC(=O)O2)O
Storage, handling
Deep frozen (-15 oC to - 20 oC)
Retest time
3 Years
Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient type
Fermentek product
Available since
Title
validated OQ2291000 RTECS
Value
yes. Maytansinol isobutyrate
Title
transport hazards
Value
NDG
Title
identity validation
Value
NMR on the lot 002 OK
Fermentek Product Category
Antibiotics
Cytotoxic agents
Research field: Cancer
Angiogenesis related
Microtubuli assembly inhibitors
Cancer Related Compounds
Anti Tumor agents
Research field: Signal Transduction
Signal to sort
A

Quote for

Price
$1.00
Ansamitocin_P3.gif
Ansamitocin_P3.gif

Herboxidiene

Herboxidiene
Molecular Formula
C25H42O6
M.W.
438.60
CAS number
142861-00-5
Source
Streptomyces chromofuscus
Fermentek product Code
HER-001
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥95% ; refer to CoA for more data
Solubility test
Clear colorless solution at 4mg/ml DMSO or EtOH
Names and identifiers

Synonyms:

Chemical names: L-glycero-L-gluco-Heptitol, 5,6-anhydro-6-C-((2S,3E,5E)-6-((2S,3S,6R)-6-(carboxymethyl)tetrahydro-3-methyl-2H-pyran-2-yl)-2-methyl-3,5-heptadienyl)-1,4,7-trideoxy-4-methyl-3-O-methyl-

IUPAC: 2-[(2R,5S,6S)-6-[(2E,4E,6S)-7-[(2R,3R)-3-[(2R,3R,4R)-4-hydroxy-3-methoxypentan-2-yl]-2-methyloxiran-2-yl]-6-methylhepta-2,4-dien-2-yl]-5-methyloxan-2-yl]acetic acid

RTECS# MJ9784800

Pubchem:  6438496

DSSTox ID: DTXSID101037297

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Customs: Other Antibiotics-29419010; Natural antibiotics, Other - 2941901050
Shipped at ambient temperature
Shipped in amber-glass vials
Fermentek Product Category
Antibiotics
Research field: Cancer
Cancer Related Compounds
Anti Tumor agents

Cylindrospermopsin

Cylindrospermopsin
Molecular Formula
C15H21N5O7S
M.W.
415.40
CAS number
143545-90-8
MSDS
Source
Cyanobacterium: Cylindrospermopsis ovalisporum
Fermentek product Code
CYL-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥ 98% ; refer to CoA for more data
Purity By TLC
≥ 98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 1mg/ml of Methanol.
Names and identifiers

 

Synonyms:

  • Cylindrospermopsin
  • 6-[(R)-Hydroxy[(2aS,3R,4S,5aS,7R)-2,2a,3,4,5,5a,6,7-octahydro-3-methyl-4-(sulfooxy)-1H-1,8,8b-triazaacenaphthylen-7-yl]methyl]-2,4(1H,3H)-pyrimidinedione

 

Chemical names:

IUPAC:  (2aS,3R,4S,5aS,7R)-7-[(R)-(2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)(hydroxy)methyl]-3-methyl-2,2a,3,4,5,5a,6,7-octahydro-1H-1,8,8b-triazaacenaphthylen-4-yl hydrogen sulfate

 

RTECS: UV9104310

 

EU number
802-929-4
Chemical name
Cylindrospermopsine
Description

Tricyclic alkaloid hepatotoxin from a cyanobacterium.

Cylindrospermopsin (abbreviated to CYN, or CYL) is a cyanotoxin produced by a variety of freshwater cyanobacteria. CYL is a polycyclic uracil derivative containing guanidino and sulfate groups. It is also zwitterionic, making it highly water soluble. CYL is toxic to liver and kidney tissue and is thought to inhibit protein synthesis and to covalently modify DNA and/or RNA.

It is not known whether cylindrospermopsin is a carcinogen, but it appears to have no tumour initiating activity in mice. (source: T3DB )

 

 

InChl Key
LHJPHMKIGRLKDR-VDPNAHCISA-N
Canonical SMILES
CC1C(CC2CC(NC3=NCC1N23)C(C4=CC(=O)NC(=O)N4)O)OS(=O)(=O)O
Isomeric SMILES
[C@@]12(C[C@@H]([C@@H]([C@@]3(N1C(N[C@](C2)([C@H](C4=CC(NC(N4)=O)=O)O)[H])=NC3)[H])C)OS(O)(=O)=O)[H]
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to the SDS for further safety and handling instructions
Ingredient type
Fermentek product
Amber-glass vial
Shipped at ambient temperature
Available since
Title
safety sources
Value
Harmful Algae Blooms in Drinking Water: Removal of Cyanobacterial Cells and ... By Harold W. Walker
Title
safety sources
Value
WHO Guidelines for Drinking-water Quality - Cyanobacterial toxins: Cylindrospermopsin
Title
LD50 oral mouse
Value
6 mg/kg
Title
safety sources
Value
https://ntp.niehs.nih.gov/ntp/htdocs/chem_background/exsumpdf/cylindrospermopsin_508.pdf
Fermentek Product Category
Cyanobacterial Toxins
Research field: Cancer
Protein synthesis inhibitors
Cancer Related Compounds
Research Area: Stem Cells
Signal to sort
C

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Price
$1.00

Fumonisin B4

Fumonisin B4
Molecular Formula
C34H59NO13
M.W.
689.83
CAS number
136379-60-7
Source
Fusarium moniliforme
Fermentek product Code
FB4-001
Brand/grade
For research
Appearance
White to off white to brown lyophilizate
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless to yellow to brown solution at 5mg/ml Methanol or 50mg/ml DMSO
Names and identifiers

Synonyms:

Chemical names:

IUPAC:

(2R,2'R)-2,2'-{[(5R,6R,7S,9S,18S,19S)-19-Amino-18-hydroxy-5,9-dimethyl-6,7-icosanediyl]bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid [ACD/IUPAC Name]

RTECS# TZ8345000

EU number
Not listed as on Aug-2023
Chemical name
(2R,2'R)-2,2'-{[(5R,6R,7S,9S,18S,19S)-19-Amino-18-hydroxy-5,9-dimethyl-6,7-icosanediyl]bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid
Description

 Fumonisin B4 is a mycotoxin of the fumonisin family. It is produced by several Fusarium and Aspergillus species. It is less abundant in the nature than the other three "main" fumonisins.  

InChl Key
WYYKRDVIBOEORL-JLCKPESSSA-N
Canonical SMILES
CCCCC(C)C(C(CC(C)CCCCCCCCC(C(C)N)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
Isomeric SMILES
CCCC[C@@H](C)[C@H]([C@H](C[C@@H](C)CCCCCCCC[C@@H]([C@H](C)N)O)OC(=O)C[C@@H](CC(=O)O)C(=O)O)OC(=O)C[C@@H](CC(=O)O)C(=O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Not hazardous for shipment
Available since
Fermentek Product Category
Mycotoxins
Cancer Related Compounds
Research field: Signal Transduction

Quote for

Price
$1.00
Fumonisin B4
Fumonisin B4

Thapsigargicin

Thapsigargicin
Molecular Formula
C32H46O12
M.W.
622.70
CAS number
67526-94-7
MSDS
Source
Thapsia garganica
Fermentek product Code
THC-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml Acetonitrile
Names and identifiers

Synonyms:
Hexanoic acid, (3S,​3aR,​4S,​6S,​6aR,​7S,​8S,​9bS)​-​6-​(acetyloxy)​-​2,​3,​3a,​4,​5,​6,​6a,​7,​8,​9b-​decahydro-​3,​3a-​dihydroxy-​3,​6,​9-​trimethyl-​8-​[[(2Z)​-​2-​methyl-​1-​oxo-​2-​buten-​1-​yl]​oxy]​-​2-​oxo-​4-​(1-​oxobutoxy)​azuleno[4,​5-​b]​furan-​7-​yl ester

Chemical names:

IUPAC:    (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-Acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methyl-2-butenoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yl hexanoate

RTECS#    Not available

 

EU number
636-165-6
Description

Hexaoxygenated tetra-acylated sesquiterpene lactone tetraester isolated from roots of Thapsia garganica; it induces mast cell degranulation and histamine release; it is an analog of thapsigargin.

InChl Key
LXWLOFYIORKNSA-FFOGNQQCSA-N
Canonical SMILES
CCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O
Isomeric SMILES
CCCCCC(=O)O[C@H]1[C@H]2C(=C([C@@H]1OC(=O)/C(=C\C)/C)C)[C@H]3[C@]([C@H](C[C@]2(C)OC(=O)C)OC(=O)CCC)([C@](C(=O)O3)(C)O)O
Compound Classification

Chemical classification: Sesquiterpene
Hexaoxygenated tetraacylated sesquiterpene lactone tetraester .

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Transport safety: Not Dangerous Goods; Not Regulated
Available since
Fermentek Product Category
Plant-derived
Cancer Related Compounds
Anti Tumor agents
Signal to sort
T

Quote for

Price
$1.00
Tomer Yemini
Tomer Yemini

Microcystin LR

Microcystin LR
Molecular Formula
C49H74N10O12
M.W.
995.17
CAS number
101043-37-2
MSDS
Source
Microcystis aeruginosa
Fermentek product Code
MLR-001
Brand/grade
For research
Appearance
White to green to blue powder
Purity by HPLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 1mg/ml Methanol
Names and identifiers

Synonyms:

  • Cyanoginosin-LR
  • Toxin T 17 
  • cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-leucyl-(3S)-3-methyl-D-β-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-γ-glutamyl]

Chemical names:

IUPAC:

RTECS GT2810000

EU number
621-323-9
Chemical name
Cyanoginosin LA, 5-L-arginine-
Description

Microcystin-LR (MC-LR) is a toxin produced by fresh water cyanobacteria. It is the most toxic of the microcystins, tumor promoter, potent and selective inhibitor of protein phosphatase 2A (PP2A). Considered to be cell-impermeable with the exception of hepatocytes which take it up via an organic anion pump. Strong hepatotoxin.

InChl Key
ZYZCGGRZINLQBL-DABAWSACSA-N
Canonical SMILES
CC1C(NC(=O)C(NC(=O)C(C(NC(=O)C(NC(=O)C(NC(=O)C(=C)N(C(=O)CCC(NC1=O)C(=O)O)C)C)CC(C)C)C(=O)O)C)CCCN=C(N)N)C=CC(=CC(C)C(CC2=CC=CC=C2)OC)C
Isomeric SMILES
C[C@H]1[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)C(=C)N(C(=O)CC[C@@H](NC1=O)C(=O)O)C)C)CC(C)C)C(=O)O)C)CCCN=C(N)N)/C=C/C(=C/[C@H](C)[C@H](CC2=CC=CC=C2)OC)/C
Solubility ( literature )

Soluble in DMSO , methanol , Ethanol.

 
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Transport safety: class 6.1 PG I
Available since
Title
Deprecated CAS
Value
128657-50-1
Fermentek Product Category
Water safety
Cyanobacterial Toxins
Regulated toxin
Protein phosphatases Inhibitors
Cancer Related Compounds
Signal to sort
M

Quote for

Price
$100,000.00
Microcystin-LR, afrer ChemidPlus
Microcystin-LR, afrer ChemidPlus

Aloe-emodin

Aloe-emodin
Molecular Formula
C15H10O5
M.W.
270.24
CAS number
481-72-1
MSDS
Source
Aloe Vera (extracted from plant)
Fermentek product Code
ALO-001
Brand/grade
For research
Appearance
Brownish-orange powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear orange solution at 50 mg/ml of DMSO
Names and identifiers

Synonyms:

* Aloe-emodin
* 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-
* 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
* 1,8-Dihydroxy-3-hydroxymethylanthraquinone
* 3-Hydroxymethylchrysazin
* Rhabarberone

 

RTECS : CB6712200

 

EU number
207-571-7
Description

Aloe-emodin is a hydroxyanthraquinone found naturally in Aloe vera and in other aloe plants. It exhibits antibacterial, antiviral, anti-inflammatory and hepatoprotective effects. recently it gains interest as a candidate anti-cancer agent.

InChl Key
YDQWDHRMZQUTBA-UHFFFAOYSA-N
Canonical SMILES
C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)CO
Compound Classification

 An anthraquinone compound from Aloe Vera and other plants.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Aloe-emodin is a drug candidate for cancer therapy.

  • It induces apoptosis in human oral squamous cell carcinoma SCC15 cells ;
  • It exerts potent anticancer effects in MIAPaCa-2 and PANC-1 human pancreatic adenocarcinoma cell lines through activation of both apoptotic and autophagic pathways, sub-G1 cell cycle arrest and disruption of mitochondrial membrane potential
  • It induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Transport safety: Not Dangerous Goods; Not Regulated
Available since
Title
from RTECS
Value
Mutagen in bacteria and mammalian cell cultures
Fermentek Product Category
Plant-derived
Cytotoxic agents
Enzyme-inhibitors
Research field: Cancer
Angiogenesis related
Apoptosis related
Protein kinase related
Cancer Related Compounds
Anti Tumor agents
Research area: Multi-drug resistance
Research Area: Stem Cells
Signal to sort
A

Quote for

Price
$10,000.00
Aloe_Emodin
Aloe_Emodin

Bleomycin sulfate

Bleomycin sulfate
Molecular Formula
C55H85N17O25S4
M.W.
1 512.62
CAS number
9041-93-4
MSDS
Source
Streptomyces verticillus
Fermentek product Code
BLE-001
Brand/grade
For research
Appearance
White to slight yellow powder
Purity by HPLC
≥95% (complex of A2, B2) ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 20mg/ml of Water,
Clear colorless solution at 20mg/ml of DMSO
Names and identifiers

Synonyms:

  • Blenoxane
  • Bleomycin B2
  • BLEOcell

Chemical names:

  • Bleomycin Sulfate (A mixture of bleomycin sulfate salts)

RTECS#     EC5991990

 
EU number
232-925-2
Description

A non-ribosomal glycopeptide antitumor antibiotic which produces single and double-strand DNA breaks in tumor cells thus  interrupting their cell cycle; has been used for the treatment of Hodgkin’s lymphoma in combination with doxorubicin, squamous cell carcinomas, testicular cancer, as well as in animal models of pulmonary fibrosis.

InChl Key
WUIABRMSWOKTOF-OCBSMOPSSA-N
Canonical SMILES
CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-]
Isomeric SMILES
CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)[O-]
Solubility ( literature )

Solubility in water 10 mg/ml; other sources: H2O: 20 mg/mL

Compound Classification
  • Chemical Classification: Glycopeptide
  • Biological classification: Antibiotics, Antineoplastic

UNSPSC: 51111701

  • E - Medical, Laboratory & Test Equipment & Supplies & Pharmaceuticals
  • 51000000 - Drugs and Pharmaceutical Products
  • 51280000 - Antibacterials
  • 51283200 - Macrolides
     
  • 51110000 - Antineoplastic agents
  • 51111700 - Antineoplastic antibiotics
  • 51111701 - Bleomycin sulphate
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Hygroscopic substance.
Protect from moisture
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Shipped in PP / PE bottle.
Available since
Title
Deleted CAS-RN
Value
134171-41-8
Title
Composition for lot BLE001:
Value
Bleomycin A2: 67.81%; Bleomycin B2: 31.62% by HPLC
Fermentek Product Category
Antibiotics
Cancer Related Compounds
Anti Tumor agents
Signal to sort
B

Quote for

Price
$1.00
Bleomycin_sulfate_complex.gif
Bleomycin_sulfate_complex.gif

Emodin

Emodin
Molecular Formula
C15H10O5
M.W.
270.24
CAS number
518-82-1
MSDS
Fermentek product Code
EMO-001
Brand/grade
For research
Appearance
Orange Powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
255°C-265°C
Solubility test
Clear yellow to red solution at 50mg/ml of DMSO;
Clear yellow to red solution at 10mg/ml of Ethanol (may need a little warming)
Names and identifiers

Synonyms

  • Archin
  • Emodol
  • Frangula emodin
  • Frangulic acid
  • Rheum emodin

 Chemical names    Emodin

RTECS                    CB7920600

EU number
208-258-8
Chemical name
Emodin
Description

 Emodin is an anthraquinone class compound. It is sourced from a plant Rheum palmatum. It exhibits antibacterial, anti-neoplastic, anti-inflammatory and anti-angiogenesis properties. 

InChl Key
RHMXXJGYXNZAPX-UHFFFAOYSA-N
Canonical SMILES
C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)O
Solubility ( literature )

Water Solubility <0.1 g/100 mL at 19ºC ; Practically insoluble in water; soluble in alcohol, aqueous alkali hydroxide solutions (cherry red color), (src: Merck index)

Compound Classification

Emodin has been investigated for the treatment of Polycystic Kidney.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature
Shipped in PP / PE bottle.
Available since
Title
phys appearance
Value
Emodin appears as orange needles or powder.
Title
CN EU 29146980
Value
Ketones and quinones; Quinones; Other; Other
Title
Usage:
Value
Only for research in the field of cancer
Title
Usage:
Value
Emodin has been investigated for the treatment of Polycystic Kidney
Fermentek Product Category
Plant-derived
Antibiotics
Angiogenesis related
Apoptosis related
Protein kinase related
Cardiovascular agents
Anti Bacterial
Cancer Related Compounds
Anti Tumor agents
Immunosupressors
Research field: Inflamation
Signal to sort
E

Quote for

Price
$10,000.00
Emodin.gif
Emodin.gif

HC toxin

HC toxin
Molecular Formula
C21H32N4O6
M.W.
436.50
CAS number
83209-65-8
MSDS
Source
Helminthosporium carbonum
Fermentek product Code
HCT-001
Brand/grade
For research
Appearance
White lyophilized powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Acetonitrile
Names and identifiers

Synonyms:

  • HC-Toxin

  • Helminthosporium Carbonum Toxin I

Chemical names:

IUPAC: (3S,6R,9S,14aR)-3,6-Dimethyl-9-{6-[(2S)-2-oxiranyl]-6-oxohexyl}decahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetrone

RTECS#

EU number
804-302-0
Chemical name
Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine)
Description

Cyclic tetrapeptide of structure cyclo(D-Pro-L-Ala-D-Ala-L-Aeo), where Aeo stands for 2-amino-9,10-epoxi-8-oxodecanoic acid. HC toxin is a potent, cell-permeable  inhibitor of histone deacetylase (HDAC).

InChl Key
GNYCTMYOHGBSBI-KVUCBBCISA-N
Canonical SMILES
CC1C(=O)NC(C(=O)N2CCCC2C(=O)NC(C(=O)N1)C)CCCCCC(=O)C3CO3
Isomeric SMILES
C[C@@H]1C(=O)N[C@H](C(=O)N2CCC[C@@H]2C(=O)N[C@H](C(=O)N1)C)CCCCCC(=O)C3CO3
Compound Classification

Cyclic oligopeptide

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Registry Numbers
Value
82653-17-6; 89363-02-0; 110114-88-0
Fermentek Product Category
Enzyme-inhibitors
Apoptosis related
Anti Mitotic
Anti Bacterial
Cancer Related Compounds
Anti Tumor agents
Others
Signal to sort
H

Quote for

Price
$100.00
HC_toxin.gif
HC_toxin.gif
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