Ansamitocin P3
Molecular Formula
C32H43ClN2O9
M.W.
635.14
CAS number
66584-72-3
MSDS
Details
Source
Actinosynnema pretoisum
Fermentek product Code
ANS-001
Brand/grade
For research
Specifications
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
190°C-198°C (decomposition)
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Chemical identification
Names and identifiers
Names and synonyms
- Maytansinol ISO-butyrate
- Antibiotic C15003P3
- Ansamitocin P-3
- Ansamitocin P3
RTECS: OQ2291000
EU number
680-663-6
Chemical name
Maytansinol isobutyrate
Description
Fungal metabolite with antimitotic, antineoplastic activity. Ansamitocin P3 binds to tubulin and inhibits vinblastine-induced spiral formation
InChl Key
OPQNCARIZFLNLF-JBHFWYGFSA-N
Canonical SMILES
CC1C2CC(C(C=CC=C(CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)CC(C4(C1O4)C)OC(=O)C(C)C)C)C)OC)(NC(=O)O2)O
Isomeric SMILES
C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)C(C)C)C)\C)OC)(NC(=O)O2)O
Further Information
Storage, handling
Deep frozen (-15 oC to - 20 oC)
Retest time
3 Years
Disclaimer
Refer to MSDS for further safety and handling instructions.
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Title
validated OQ2291000 RTECS
Value
yes. Maytansinol isobutyrate
Title
transport hazards
Value
NDG
Title
identity validation
Value
NMR on the lot 002 OK
Fermentek Product Category
Signal to sort
A
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