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Ochratoxin A – A Mycotoxin Found in Food and Beyond

Ochratoxin A (OTA) is a mycotoxin produced by several species of Aspergillus and Penicillium fungi and is considered the most toxic of all the other ochratoxins. It is a secondary metabolite that contaminates various food and feed products, posing significant health risks to…

7-Aminoactinomycin D (7-AAD): A Vital Tool in Cell Viability Assays

In the realm of cellular biology, accurate assessment of cell viability is crucial for numerous applications, ranging from basic research to clinical diagnostics. One of the key reagents employed in these assessments is 7-Aminoactinomycin D (7-AAD), an Actinomycin D (AD) analog.…

Salinomycin, A multi-targeted "Magic Bullet" - Uses, Benefits and Implications

Salinomycin (SAL) is a polyether ionophore antibiotic widely used in the agricultural industry, particularly in poultry and cattle farming. Salinomycin was discovered in the 1970s, and has become an essential tool in animal husbandry due to its potent antibacterial, antifungal,…

Deoxynivalenol: Risks, Impact, and Management Strategies

Deoxynivalenol (DON), also known as Vomitoxin, is a type of mycotoxin produced by certain species of Fusarium fungi, primarily Fusarium graminearum and Fusarium culmorum. These fungi commonly infect cereal grains such as wheat, barley, oats, and corn, posing significant…

Understanding Cytochalasin D: Applications, Mechanisms and Implications.

 Cytochalasin D is a member of the class of mycotoxins known as Cytochalasins (cytos=cell, chalasis = relaxation), isolated in 19671. Four Cytochalasins were isolated: Cytochalasin A and B from helminthosporium dematioideum, while Cytochalasin C and D from …