Daptomycin

Molecular Formula

C72H101N17O26

M.W.

620.67

Details

Source

Streptomyces sp.

Fermentek product Code

DAP-001

Brand/grade

For research

Specifications

Appearance

Off-white to yellow powder

Purity by HPLC

≥95% ; refer to CoA for more data

Melting point

200°C-210°C

Solubility test

Clear colorless to faint yellow solution at 5mg/ml of Water or 25 mg/ml of Methanol

Chemical identification

Names and identifiers

Synonyms:

Cubicin
Dapzura RT
Cidecin

Chemical names:

Structure as peptide

N-Decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine[egr]1-lactone

ECHA:

600-389-2

IUPAC:

RTECS#

Description

Lipopeptide antibacterial antibiotic

InChl Key

DOAKLVKFURWEDJ-RWDRXURGSA-N

Canonical SMILES

CCCCCCCCCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]1C(=O)NCC(=O)N[C@@H](CCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@@H]([C@H](C)CC(=O)O)C(=O)N[C@@H](CC(=O)c2ccccc2N)C(=O)O[C@@H]1C

Isomeric SMILES

CCCCCCCCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H]3[C@H](OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)[C@H](C)CC(=O)O)CC(=O)C4=CC=CC=C4N)C

Further Information

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Other vendors may recommend higher temperatures for storage.

Protect from moisture!

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals