Pyripyropene A
Molecular Formula
C31H37NO10
M.W.
583.60
CAS number
147444-03-9
Details
Source
Eupenicillium reticulisporum
Fermentek product Code
PYR-001
Brand/grade
For research
Specifications
Appearance
Yellow powder
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
159-165C
Solubility test
Clear yellow solution at 10mg/ml of Methanol
Chemical identification
Names and identifiers
Synonyms:
FO 1289A
(3S,4R,4aR,6S,6aS,12R,12aS,12bS)-4-(Acetoxymethyl)-12-hydroxy-4,6a,12b-trimethyl-11-oxo-9-(pyridin-3-yl)-1,2,3,4,4a,5,6,6a,11,12,12a,12b-dodecahydrobenzo[f]pyrano[4,3-b]chromene-3,6-diyl diacetate
Chemical names:
2H,11H-Naphtho(2,1-b)pyrano(3,4-e)pyran-11-one,1,3,4,4a,5,6a,12,12a,12b-decahydro-4-((acetyloxy)methyl)-3,6-bis(acetyloxy)-12-hydroxy-9-(3-pyridinyl)-4,6a,12b -trimethyl-
IUPAC:
[(1S,2S,5S,6R,7R,9S,10S,18R)-5,9-diacetyloxy-18-hydroxy-2,6,10-trimethyl-16-oxo-14-pyridin-3-yl-11,15-dioxatetracyclo[8.8.0.02,7.012,17]octadeca-12(17),13-dien-6-yl]methyl acetate
RTECS# QL6289000
EU number
813-163-5
Description
Pyripyropene A is a highly specific inhibitor of acyl-coenzyme A cholesterol acetyltransferase 2 (ACAT2).
InChl Key
PMMQOFWSZRQWEV-RVTXXDJVSA-N
Canonical SMILES
CC(=O)OCC1(C(CCC2(C1CC(C3(C2C(C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)OC(=O)C)C)OC(=O)C)C
Isomeric SMILES
CC(=O)OC[C@@]1([C@H](CC[C@]2([C@H]1C[C@@H]([C@@]3([C@@H]2[C@H](C4=C(O3)C=C(OC4=O)C5=CN=CC=C5)O)C)OC(=O)C)C)OC(=O)C)C
Further Information
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3Y
Applications
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Composition
Ingredient type
Fermentek product
Supply related information
Customs: Other Antibiotics-29419000
Shipped at ambient temperature
Transport safety: Not Dangerous Goods; Not Regulated
Other Fields
Image
Image
