Pepstatin A
Molecular Formula
C34H63N5O9
M.W.
685.89
CAS number
26305-03-3
Details
Source
Synthetic
Fermentek product Code
PEP-001
Brand/grade
For research
Specifications
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 5mg/ml DMSO or 1mg/ml Methanol
Chemical identification
Names and identifiers
Synonyms:
- Pepstatin A
- Pepstatin
- Ahpatinin C
Formula as a peptide:
- Isovaleryl-Val-Val-Sta-Ala-Sta-OH
- N-Isovaleryl-L-valyl-L-valyl-3-hydroxy-6-methyl-gamma-aminoheptanoyl-L-alanyl-3-hydroxy-6-methyl-gamma-aminoheptanoic acid
Chemical names:
IUPAC:
- N-(3-methylbutanoyl)-L-valyl-N-[(3S,4S)-1-{[(2S)-1-{[(2S,3S)-1-carboxy-2-hydroxy-5-methylhexan-3-yl]amino}-1-oxopropan-2-yl]amino}-3-hydroxy-6-methyl-1-oxoheptan-4-yl]-L-valinamide
RTECS#
SC6155000
EU number
247-600-0
Description
Pepstatin A is a pentapeptide antibiotic, isolated from Streptomyces species. It is a potent inhibitor of aspartyl proteases.
InChl Key
FAXGPCHRFPCXOO-LXTPJMTPSA-N
Canonical SMILES
CC(C)CC(C(CC(=O)O)O)NC(=O)C(C)NC(=O)CC(C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)CC(C)C)O
Isomeric SMILES
C[C@@H](C(=O)N[C@@H](CC(C)C)[C@H](CC(=O)O)O)NC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C)O
Further Information
Solubility ( literature )
In DMSO: 5mg/cc
In Methanol: 1 mg/cc
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Composition
Ingredient type
Fermentek product
Supply related information
Shipped at ambient temperature
Other Fields
Image
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