Altertoxin I

Altertoxin I
Molecular Formula
C20H16O6
M.W.
352.34
CAS number
56258-32-3
MSDS
Source
Alternaria sp.
Fermentek product Code
ALX-001
Brand/grade
For research
Appearance
Off-White to yellowish powder
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear slight yellow solution at 10mg/ml Methanol
Names and identifiers

Synonyms:

  • (12S,12As,12Br)-4,9,12,12B-Tetrahydroxy-2,11,12,12A-Tetrahydro-1H-Perylene-3,10-Quinone;
  • Altertoxin I
  • Altertoxin-I

Chemical names:

IUPAC:

  • (12S,12aS,12bR)-4,9,12,12b-tetrahydroxy-2,11,12,12a-tetrahydro-1H-perylene-3,10-dione

 

RTECS#   : BC9625200

Description

Altertoxin-1, a natural mycotoxin from Alternaria fungi, an important contaminant in cereals, vegetables.

InChl Key
GJIALGLHOBXNAT-KPOBHBOGSA-N
Canonical SMILES
C1CC2(C3C4C(O4)C(=O)C5=C(C=CC(=C35)C6=C2C(=C(C=C6)O)C1=O)O)O
Isomeric SMILES
C1C[C@]2([C@@H]3[C@H](CC(=O)C4=C(C=CC(=C34)C5=C2C(=C(C=C5)O)C1=O)O)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Altertoxin I (and other altertoxins) inhibit the HIV replication.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
tsa
Value
V=veg fermentation
Title
classif
Value
cytotoxic; mutagenic
Fermentek Product Category
Food Safety
Mycotoxins
Alternaria toxins
Cytotoxic agents
Enzyme-inhibitors
Research field: Cancer
Anti Viral
DNA replication inhibitors
Signal to sort
A

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Price
$1.00
Altertoxin_I.gif
Altertoxin_I.gif

Destruxin A

Destruxin A
Molecular Formula
C29H47N5O7
M.W.
577.71
CAS number
6686-70-0
Source
Metarhizium anisopliae
Fermentek product Code
DSA-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥96% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
122°C-128°C
Solubility test
Clear colorless solution at 10mg/ml of Dichloromethane;
Clear colorless solution at 10mg/ml of DMSO
Names and identifiers

Synonyms:

Chemical names:

IUPAC:  (3S,6S,9S,16R,21aS)-16-Allyl-3-[(2S)-2-butanyl]-6-isopropyl-5,8,9-trimethyldodecahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-1,4,7,10,14,17(11H,16H)-hexone 

RTECS# HH1500000

EU number
636-280-1
Description

Destruxins are metabolites of a fungus Metarhizium anisopliae. Chemically, these substances are classified as  cyclic hexa-depsipeptides. They posess insecticidal, anti-viral, and phytotoxic propereties. Recently, there is also growing interest in their toxicity to cancer cells.

InChl Key
XIYSEKITPHTMJT-UHFFFAOYSA-N
Canonical SMILES
CCC(C)C1C(=O)N(C(C(=O)N(C(C(=O)NCCC(=O)OC(C(=O)N2CCCC2C(=O)N1)CC=C)C)C)C(C)C)C
Compound Classification

chemical:

Natural cyclic depsipeptide 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Research field: Cancer
Anti Viral
Immunomodulators
Signal to sort
D

Quote for

Price
$1.00
Destruxin_A.gif
Destruxin_A.gif

Equisetin

Equisetin
Molecular Formula
C22H31NO4
M.W.
373.49
CAS number
57749-43-6
MSDS
Source
Fusarium equiseti
Fermentek product Code
EQU-001
Brand/grade
For research
Appearance
Light tan to tan or off-white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10 mg/ml of Methanol or DMSO
Names and identifiers

IUPAC:

(2S)-4-({(1S,2R,4aS,6R,8aR)-1,6-Dimethyl-2-[(1E)-1-propen-1-yl]-1,2,4a,5,6,7,8,8a-octahydro-1-naphthalenyl}carbonyl)-5-hydroxy-2-(hydroxymethyl)-1-methyl-1,2-dihydro-3H-pyrrol-3-one

RTECS KD7986000

EU number
303-396-6
Description

Antibiotic from Fusarium equiseti; derivative of N-methyl-2,4-pyrollidone

InChl Key
QNQBPPQLRODXET-HMHJLHGTSA-N
Canonical SMILES
CC=CC1C=CC2CC(CCC2C1(C)C(=C3C(=O)C(N(C3=O)C)CO)O)C
Isomeric SMILES
C/C=C/[C@@H]1C=C[C@@H]2C[C@@H](CC[C@H]2[C@]1(C)/C(=C\3/C(=O)[C@@H](N(C3=O)C)CO)/O)C
Solubility ( literature )

Equisetin is reported to be soluble in DMF or DMSO, moderately soluble in methanol or ethanol and poorly soluble in water.

Equisetin solubility as reported in an original patent,

  • in acetone of 660 mg./ml.,
  • in ethanol of 330 mg./ml.,
  • in methanol of 220 mg./ml.,
  • in hexane of 0.8 mg./ml.,
  • in water of 0.3 mg./ml.

Elemental analysis: C, 70.95; H, 8.39; N, 3.14;

Compound Classification

Chemical classification:

Tetramic acid class antibiotic.

Classification by Bioactivity:

HIV-integrase inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Equisetin inhibits some ATPases, and affects several energy related mitochondrial enzymes.

Equisetin was also shown to inhibit (in-vitro) HIV-1 integrase.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Amber-glass vial.
Available since
Title
Transport
Value
Not regulated
Title
Animal rawmat
Value
No
Fermentek Product Category
Antibiotics
Enzyme-inhibitors
Anti Bacterial
Anti Viral
Signal to sort
E

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Price
$1.00
Equisetin.gif
Equisetin.gif

Tunicamycin (complex)

Tunicamycin (complex)
Molecular Formula
C39H64N4O16 (for n=10, "Tunicamycin VII")
CAS number
11089-65-9
MSDS
Source
Streptomyces chartreusis
Fermentek product Code
TUN-001
Brand/grade
For research
Appearance
Off white to tan powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
4 spots matching standard, no other spots, by multiple methods.
Melting point
≥210°C
Solubility test
Clear solution at 5mg/ml of Methanol,
Clear solution at 50mg/ml of DMSO
Names and identifiers

RTECS: YO7980200

EU number
601-012-4
Description

Tunicamycin is a mixture of homologous nucleoside antibiotics.
The main homologs differ in the length of the fatty chain moiety.
The following table defines the four main Tunicamycin homologs.

  • Tunicamycin A, aka Tunicamycin V, n=9, mw=817;
  • Tunicamycin B, aka Tunicamycin VII, n=10, mw=831;
  • Tunicamycin C, aka Tunicamycin II, n=8, mw=845;
  • Tunicamycin D, aka Tunicamycin X, n=11, mw=859
Solubility ( literature )
  • Tunicamycin is soluble in DMSO, alkaline water, hot methanol.
  • Practically insoluble in acetone, ethyl acetate.
  • Unstable in acidic solutions
Compound Classification
  • nucleoside antibiotic
  • antiviral
  • inhibitor of glucosylation of proteins
  • tunicamycin causes cell cycle arrest in G1 phase
  • Tunicamycin has anti-angiogenesis properties.
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Tunicamycins inhibit protein glycosylation. They arrest cell cycle in late G1As Tunicamycin affects cell membrane permeability, it was shown to increase production of antibiotics, such as streptomycin PRODUCT USE A tool to study glycoprotein synthesis in a wide variety of biological systems. Family of nucleoside antibiotics produced by Streptomyces lysosuperificus. Tunicamycin interferes with glycoprotein synthesis in yeast and mammalian systems and enhances antiviral and anticellular activity of interferon. Possesses cell - surface altering activity. Inhibits the transfer of N-acetylglucosamine-1-phosphate from UDP -N- acetylglucosamine to dolichol monophosphate and thereby blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi and viruses.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg II
Title
Deleted CAS Registry Numbers
Value
11118-26-6
Fermentek Product Category
Antibiotics
Enzyme-inhibitors
Research field: Cancer
Angiogenesis related
Protein kinase related
Anti Bacterial
Anti Viral
Research field: Signal Transduction
Signal to sort
T

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Price
$1.00

Thapsigargin

Thapsigargin
Molecular Formula
C34H50O12
M.W.
650.75
CAS number
67526-95-8
MSDS
Source
Thapsia garganica
Fermentek product Code
THP-001
Brand/grade
For research
Appearance
White to faint yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml Acetonitrile
Names and identifiers

Synonyms: octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester

RTECS  RH0352700 

EU number
614-076-3
Description

Thapsigargin is a cell-permeable, tumor promoting sesquiterpene lactone. A tight-binding inhibitor of intracellular calcium (SERCA) pumps (sarco/endoplasmic reticulum Ca2+ ATPase). Chemically it is classified as a sesquiterpene lactone antibiotic.

A study from the University of Nottingham showed promising results for its use against Covid-19 and other coronavirus.

 

InChl Key
IXFPJGBNCFXKPI-FSIHEZPISA-N
Canonical SMILES
CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O
Isomeric SMILES
CCCCCCCC(=O)O[C@H]1[C@H]2C(=C([C@@H]1OC(=O)/C(=C\C)/C)C)[C@H]3[C@]([C@H](C[C@]2(C)OC(=O)C)OC(=O)CCC)([C@](C(=O)O3)(C)O)O
Solubility ( literature )

DMSO, Acetonitril, Ethanol, Methanol, Dichloromethane

Compound Classification
  • Sesquiterpene lactone
  • SERCA inhibitor
  • Apoptosis related antibiotic
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Hygroscopic substance.
Protect from moisture
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Title
TSE category
Value
V
Fermentek Product Category
Plant-derived
Cytotoxic agents
Apoptosis related
Anti Viral
Cancer Related Compounds
Anti Tumor agents
Signal to sort
T

Quote for

Price
$1.00
Thapsigargin.gif
Thapsigargin.gif

Tenuazonic acid (Cu salt)

Tenuazonic acid – Copper salt
Molecular Formula
C20H28CuN2O6
M.W.
455.99
CAS number
76569-74-9
MSDS
Source
Alternaria sp.
Fermentek product Code
TNZ-001
Brand/grade
For research
Appearance
Light blue-greenish powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear blue-green solution at 10mg/ml Dichloromethane
Names and identifiers

Synonyms:

  • 3-Pyrrolin-2-one, 3-acetyl-5-sec-butyl-4-hydroxy-, L-

RTECS: UY7425000
 

 

Description

Tenuazonic acid is a natural mycotoxin, inhibitor of protein synthesis. Tenuazonic acid is offered as its Cuprum salt. 

 

InChl Key
LLXUERDQXVXQAY-UHFFFAOYSA-N
Canonical SMILES
CCC(C)C1C(=C(C(=O)N1)C(=O)C)O.CCC(C)C1C(=C(C(=O)N1)C(=O)C)O.[Cu]
Solubility ( literature )

Soluble in DMSO, pure ethanol, methanol

Compound Classification
  • Pyrrolidinone mycotoxin
  • Tenuazonic Acid Copper Salt is an antineoplastic agent and mycotoxin. It Inhibits protein synthesis, though which it has been shown inhibiting TPA-induced ornithine decarboxylase activity. Lack of ornithine decarboxylase has been shown to eventually cause DNA damage induced apoptosis. It has also been shown to inhibit photosystem II.
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

This is a potential antineoplastic agent

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg III
Fermentek Product Category
Mycotoxins
Alternaria toxins
Cytotoxic agents
Research field: Cancer
Apoptosis related
Anti Bacterial
Anti Viral
Anti Tumor agents
Signal to sort
T

Quote for

Price
$1.00
Tenuazonic_acid__Cu_salt_.gif
Tenuazonic_acid__Cu_salt_.gif

Sinefungin

Sinefungin
Molecular Formula
C15H23N7O5
M.W.
381.39
CAS number
58944-73-3
MSDS
Source
Streptomyces sp.
Fermentek product Code
SN
Brand/grade
For research
Appearance
White to yellow powder
Purity by HPLC
≥96% ; refer to CoA for more data
Purity By TLC
≥96% ; refer to CoA for more data
Solubility test
Clear colorless solution at 20mg/ml of water
Names and identifiers

Synonym:

RTECS: HE3140000

UPAC Name: (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid

 

 
EU number
637-385-5
Description

Natural antibiotic containing adenine, sugar hydroxyl and amino groups; exhibiting Antifungal ,Antimalarial and Antiprotozoal properties.

InChl Key
LMXOHSDXUQEUSF-YECHIGJVSA-N
Canonical SMILES
C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CC(CCC(C(=O)O)N)N)O)O
Isomeric SMILES
C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)N)O)O
Solubility ( literature )

Good water solubility. Soluble in ethanol, methanol, DMF or DMSO (lit.)

Compound Classification

Chemical class:

  • Adenosine analog
  • Nucleoside antibiotic

Biological activity:

  • Antifungal 
  • Antimalarial
  • Antiprotozoal

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Applications

Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2 Antifungal Antimalarials Antiprotozoal

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Title
toxicity by RTECS oral mouse LD50
Value
1 gram/kg
Fermentek Product Category
Antibiotics
Anti Protozoal
Anti Bacterial
Anti Viral
Research field: Signal Transduction
Signal to sort
S

Quote for

Price
$1.00
Sinefungin.gif
Sinefungin.gif

Mithramycin A

Mithramycin A
Molecular Formula
C52H76O24
M.W.
1 085.00
CAS number
18378-89-7
MSDS
Source
Streptomyces argillaceus
Fermentek product Code
MTA-001
Brand/grade
For research
Appearance
Yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
175°C-185°C
Solubility test
Clear yellowish solution at 100mg/ml DMSO
Names and identifiers

Synonyms:

  • Mithramycin
  • Plicamycin
  • Aureolic acid

RTECS: PZ2800000

EU number
634-048-4
Description

Oligosaccharide antibiotic, a RNA synthesis inhibitor.

InChl Key
CFCUWKMKBJTWLW-BKHRDMLASA-N
Canonical SMILES
CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O
Isomeric SMILES
C[C@@H]1[C@H]([C@@H](C[C@@H](O1)O[C@@H]2C[C@@H](O[C@@H]([C@H]2O)C)OC3=CC4=CC5=C(C(=O)[C@H]([C@@H](C5)[C@@H](C(=O)[C@H]([C@@H](C)O)O)OC)O[C@H]6C[C@H]([C@@H]([C@H](O6)C)O)O[C@H]7C[C@H]([C@H]([C@H](O7)C)O)O[C@H]8C[C@]([C@@H]([C@H](O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O
Solubility ( literature )

DMSO, Methanol, Ethanol

Compound Classification

Anthracycline Pentaglycosidic antibiotic.

RNA synthesis inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

DNA binding fluorescent dye. Until 2000 it was used to reduce high levels of plasma calcium. Used as an antineoplastic agent in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not dangerous goods
Title
Deleted CAS numbers
Value
1395-17-1; 1403-98-1; 12708-66-6; 12708-67-7; 23973-19-5; 97666-60-9; 219612-19-8; 744999-90-4; 807260-73-7; 826336-23-6; 899900-19-7; 1195235-16-5
Title
CN code
Value
29419000
Title
toxicity by RTECS
Value
LD50 oral mouse 500 mg/kg
Title
toxicity by RTECS
Value
TDLo oral human 50 ug/kg* 5D
Title
EPA USA status
Value
EPA GENETOX PROGRAM 1988, Positive: CHO gene mutation
Fermentek Product Category
Antibiotics
Research field: Cancer
Angiogenesis related
Anti Viral
Cancer Related Compounds
DNA replication inhibitors
Immunomodulators
Signal to sort
M

Quote for

Price
$1.00
Mithramycin_A.gif
Mithramycin_A.gif

Hypericin

Hypericin
Molecular Formula
C30H16O8
M.W.
504.44
CAS number
548-04-9
Source
Hypericium perforatum (plant extract)
Fermentek product Code
HYP-001
Brand/grade
For research
Appearance
Blue – black powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear red solution at 10mg/ml DMSO
Names and identifiers
  • Cyclo-Werrol
EU number
208-941-0
Description

Natural antidepressant. Anti-retroviral agent. A protein kinaze-C inhibitor.

InChl Key
BTXNYTINYBABQR-UHFFFAOYSA-N
Canonical SMILES
CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O
Solubility ( literature )

Soluble in alkaline aqueous solutions. Soluble in organic bases such as pyridine (red fluorescent solutions) but not in other organic solvents

Compound Classification
  • Perylene analog.
  • Anthraquinone derivative
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Retest time
3 Years
Applications

Antidepressant. Apoptosis inducer. PKC inhibitor. Antiviral

Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient type
Fermentek product
Available since
Title
Deleted CAS numbers
Value
345224-62-6; 693273-27-7;935869-37-7
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Plant-derived
Research field: Cancer
Protein kinase related
Anti Viral
Cancer Related Compounds
Immunosupressors
Immunomodulators
Signal to sort
H

Quote for

Price
$1.00
Hypericin.gif
Hypericin.gif

Gliotoxin

Gliotoxin
Molecular Formula
C13H14N2O4S2
M.W.
326.39
CAS number
67-99-2
MSDS
Source
Gliocladium fimbriatum
Fermentek product Code
GLI-001
Appearance
White to yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
200°C-206°C
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms

  • Aspergillin
  • IUPAC name : (3R,6S,10aR)-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3,6,10-tetrahydro-5aH-3,10a-epidithiopyrazino[1,2-a]indole-1,4-dione
  • IUPAC name : Gliotoxin

RTECS KB4725000

 

 

 

Description

Gliotoxin is a fungal antibiotic mycotoxin with antiphagycytic and immunomodulatory activities.

Gliotoxin is  an antibiotic that is toxic to higher animals as well as to animal and plant pathogens and that is produced by various fungi (as of the genera Gliocladium, Aspergillus, andPenicillium)

InChl Key
FIVPIPIDMRVLAY-RBJBARPLSA-N
Canonical SMILES
CN1C(=O)C23CC4=CC=CC(C4N2C(=O)C1(SS3)CO)O
Isomeric SMILES
CN1C(=O)[C@]23CC4=CC=C[C@@H]([C@H]4N2C(=O)[C@]1(SS3)CO)O
Solubility ( literature )

DMSO, Methanol, Ethanol, Ethyl acetate, Petrol-ether, Dichloromethane. Water insoluble

Compound Classification

Chemical class:

  • Indole mycotoxin

Bioactivity class:

  • Immunomodulator
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Hygroscopic substance.
Protect from moisture
Protect from light !
Avoid exposing to strong direct light.
Retest time
3 Years
Applications

Gliotoxin blocks the thiol groups in the membranes . Gliotoxin induces apoptotsis in macrophages and thymocytes. Gliotoxin induces Ca2+ release from intact rat liver mitochondria.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg III
Title
CN code
Value
29419000
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Apoptosis related
Anti Viral
Immunomodulators
Signal to sort
G

Quote for

Price
$1.00
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Gliotoxin.gif
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