Synonyms: Zygosporin A
Chemical Name: (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)- 7,18-dihydroxy-16,18-dimethyl-10-phenylcytochalasa-6(12),13,19-triene-1,17-dione
RTECS : RN9781000
Cytochalasins are a group of about 20 known mycotoxins, which affect actin stress fibers, causing actin depolymerization.Cytochalasin D is a cell-permeable mycotoxin, which causes both the association and dissociation of actin subunits. Cytochalasin D disrupts actin filaments and inhibits actin polymerization.
DMSO, Ethanol, Methanol
- Macrolide indol mycotoxin
- Actin inhibitor
Cytochalasins are used as tools in cytological research, and in the field of actin polymerization. Cytochalasin D is 10 times more effective than cytochalasin B and does not inhibit glucose transport across cell membranes.