Cytochalasin D

Molecular Formula

C30H37NO6

M.W.

507.62

CAS number

22144-77-0

MSDS

Download

Details

Source

Zygosporium mansonii

Fermentek product Code

CYD-001

Brand/grade

For research

Specifications

Appearance

White powder

Purity by HPLC

≥97% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

230°C-245°C

Solubility test

Clear colorless solution at 25mg/ml DMSO, Clear colorless solution at 5mg/ml Ethanol

Chemical identification

Names and identifiers

Synonyms: Zygosporin A

Chemical Name: (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)- 7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-triene-1,17-dione

EU number

244-804-1

Description

Cytochalasin D is a cell permeable mycotoxin, which causes both the association and dissociation of actin subunits. Cytochalasin D disrupts actin filaments and inhibits actin polymerization.

InChl Key

SDZRWUKZFQQKKV-JHADDHBZSA-N

Canonical SMILES

CC1CC=CC2C(C(=C)C(C3C2(C(C=CC(C1=O)(C)O)OC(=O)C)C(=O)NC3CC4=CC=CC=C4)C)O

Isomeric SMILES

C[C@H]1C/C=C/[C@H]2[C@@H](C(=C)[C@H]([C@@H]3[C@@]2([C@@H](/C=C/[C@@](C1=O)(C)O)OC(=O)C)C(=O)N[C@H]3CC4=CC=CC=C4)C)O

Further Information

Solubility ( literature )

DMSO, Ethanol, Methanol

Compound Classification

Macrolide indol mycotoxin
Cytochalasin
Actin inhibitor

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Protect from moisture

Open carefully.

Use the original container to store the product.

Avoid exposing to strong direct light.

Store under argon.

Other vendors may recommend higher temperatures for storage.

Retest time

3 Years

Applications

Cytochalasins are used as tools in cytological research, and in the field of actin polymerization. Cytochalasin D is 10 times more effective than cytochalasin B and does not inhibit glucose transport across cell membranes.

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Composition

Ingredient type

Fermentek product

Special Info

Available since

1998