Angiogenesis is a process of creating new blood vessels in the body. Angiogenesis is a key factor in the development of hard cancers, which depend on a constantly growing supply of blood as they enlarge. Other diseases can be caused by insufficient blood supply to certain organs.

Among such conditions are diabetic ulcers, miscellaneous skin lesions, cardio-vascular diseases, and cerebrovascular events. It is believed that controlling the process of angiogenesis could lead to the development of therapies for such conditions.

Tunicamycin (complex)

Tunicamycin (complex)
Molecular Formula
C39H64N4O16 (for n=10, "Tunicamycin VII")
CAS number
11089-65-9
MSDS
Source
Streptomyces chartreusis
Fermentek product Code
TUN-001
Brand/grade
For research
Appearance
Off white to tan powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
4 spots matching standard, no other spots, by multiple methods.
Melting point
≥210°C
Solubility test
Clear solution at 5mg/ml of Methanol,
Clear solution at 50mg/ml of DMSO
Names and identifiers

RTECS: YO7980200

EU number
601-012-4
Description

Tunicamycin is a mixture of homologous nucleoside antibiotics.
The main homologs differ in the length of the fatty chain moiety.
The following table defines the four main Tunicamycin homologs.

  • Tunicamycin A, aka Tunicamycin V, n=9, mw=817;
  • Tunicamycin B, aka Tunicamycin VII, n=10, mw=831;
  • Tunicamycin C, aka Tunicamycin II, n=8, mw=845;
  • Tunicamycin D, aka Tunicamycin X, n=11, mw=859
Solubility ( literature )
  • Tunicamycin is soluble in DMSO, alkaline water, hot methanol.
  • Practically insoluble in acetone, ethyl acetate.
  • Unstable in acidic solutions
Compound Classification
  • nucleoside antibiotic
  • antiviral
  • inhibitor of glucosylation of proteins
  • tunicamycin causes cell cycle arrest in G1 phase
  • Tunicamycin has anti-angiogenesis properties.
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Tunicamycins inhibit protein glycosylation. They arrest cell cycle in late G1As Tunicamycin affects cell membrane permeability, it was shown to increase production of antibiotics, such as streptomycin PRODUCT USE A tool to study glycoprotein synthesis in a wide variety of biological systems. Family of nucleoside antibiotics produced by Streptomyces lysosuperificus. Tunicamycin interferes with glycoprotein synthesis in yeast and mammalian systems and enhances antiviral and anticellular activity of interferon. Possesses cell - surface altering activity. Inhibits the transfer of N-acetylglucosamine-1-phosphate from UDP -N- acetylglucosamine to dolichol monophosphate and thereby blocks the formation of N-glycosidic protein-carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi and viruses.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg II
Title
Deleted CAS Registry Numbers
Value
11118-26-6
Fermentek Product Category
Antibiotics
Enzyme-inhibitors
Research field: Cancer
Angiogenesis related
Protein kinase related
Anti Bacterial
Anti Viral
Research field: Signal Transduction
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T

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Thiolutin

Thiolutin
Molecular Formula
C8H8N2O2S2
M.W.
228.29
CAS number
87-11-6
Source
Streptomyces luteosporeus
Fermentek product Code
THL-001
Brand/grade
For research
Appearance
Yellow powder
Purity by HPLC
≥97% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear yellow solution at 1mg/ml DMSO
Names and identifiers

RTECS JP1355000

Farcinicin,

Propiopyvothine,

Acetopyrrothine

Description

Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability. Studies have shown that thiolutin inhibits adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin and thus suppresses tumor cell-induced angiogenesis in vivo.

InChl Key
MHMRAFONCSQAIA-UHFFFAOYSA-N
Canonical SMILES
CC(=O)NC1=C2C(=CSS2)N(C1=O)C
Solubility ( literature )

Thiolutin is soluble in Dichloromethane or Methanol, DMSO (0.5%)Water solubility: 0.2 gram /Liter

Compound Classification

dithiolopyrrolonePyrrolidinone antibioticRNA polymeraseinhibitorangiogenesis inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Protect from moisture! Hygroscopic substance.
Retest time
3 Years
Applications

Inhibitor of DNA-primed RNA polimerase and DNA polimerase. Apoptosis inducer. Antineoplastic drug

Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg II
Fermentek Product Category
Antibiotics
Angiogenesis related
Signal to sort
T

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$1.00
Thiolutin.gif
Thiolutin.gif

Radicicol

Radicicol
Molecular Formula
C18H17O6Cl
M.W.
364.78
CAS number
12772-57-5
Source
Humicola grisea
Fermentek product Code
RAD-001
Brand/grade
For research
Appearance
white to light yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
190°C-199°C
Solubility test
Clear colorless solution at 20mg/ml DMSO
Names and identifiers

Synonyms:

  • Monorden
  • (2Z,4E)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione

RTECS: RR1105000

EU number
642-889-3
Description

Radicicol is a macrolactone antibiotic. Radicicol is a tyrosine kinase inhibitor. It displays anti-angiogenic activity.

InChl Key
YZWZEOGROVVHK-GTMNPGAYSA-N
Canonical SMILES
CC1CC2C(O2)C=CC=CC(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1
Isomeric SMILES
C[C@@H]1C[C@@H]2[C@H](O2)/C=C\C=C\C(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1
Solubility ( literature )

Methanol, Ethanol, DMSO.

Compound Classification
  • macrolactone
  • tyrosine kinase inhibitor
  • angiogeniesis inhibitor
  • HSP90 inhibitor
  • Anti fungal
  •  
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Avoid exposing to strong direct light.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Antibiotics
Enzyme-inhibitors
HSP90 inhibitors
Angiogenesis related
Protein kinase related
Anti Fungal
Anti Protozoal
Signal to sort
R

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$1.00
Radicicol.gif
Radicicol.gif

PKC412

PKC412 (Midostaurin)
Molecular Formula
C35H30N4O4
M.W.
570.60
CAS number
120685-11-2
Source
Synthetic
Fermentek product Code
PKC-001
Brand/grade
For research
Appearance
White to off-white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
225°C-235°C
Solubility test
Clear colorless solution at 10mg/ml DMSO; Clear colorless solution at 5mg/ml methanol
Names and identifiers

Synonyms:

  • Midostaurin
  • PKC412
  • Benzoylstaurosporine
  • 4'-N-Benzoylstaurosporine

Commercial names: 

  • Rydapt

RTECS: CV5045180

Chemical name
4'-N-benzoyl staurosporine
Description

PKC412 (Midostaurin) is a cell permeable inhibitor of protein kinases, including protein kinase-C.

InChl Key
BMGQWWVMWDBQGC-UHFFFAOYSA-N
Canonical SMILES
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Solubility ( literature )

Soluble in DMSO, Dichloromethane.
Water solubility : < 0.1 mg/1

Compound Classification
  • indolocarbazole alkaloid
  • PKC inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Protect from moisture! Hygroscopic substance.
Retest time
3 Years
Applications
  • PKC412 is mentioned as a specific treatment for Myeloproliferative Disease (MPD)
  • PKC412 selectively inhibits protein kinase C (PKC)
  • Investigated for use/treatment in adult patients with high-risk acute myeloid leukemia (AML)
Disclaimer
Semi-Synthetic.
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Research field: Cancer
Angiogenesis related
Protein kinase related
Cancer Related Compounds
Research field: Signal Transduction
Others
Signal to sort
P

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PKC412__Midostaurin_.gif
PKC412__Midostaurin_.gif

Paclitaxel (Taxol)

Paclitaxel (Taxol)
Molecular Formula
C47H51NO14
M.W.
853.90
CAS number
33069-62-4
Source
Taxus brevifolia ( a plant extract)
Fermentek product Code
PAC-001
Brand/grade
For research
Appearance
White crystalline solid.
Purity by HPLC
≥ 98% ; refer to CoA for more data
Melting point
200°C to 220°C (decomposition)
Solubility test
Clear colorless solution at 50mg/ml of Methanol.
Names and identifiers

RTECS: DA8340700

EU number
608-826-9
Description

Paclitaxel (taxol) is an antineoplastic agent from a plant extract.

Paclitaxel  (taxol) stabilizes microtubules in their polymerized form thus leading to cell death

InChl Key
RCINICONZNJXQF-MZXODVADSA-N
Canonical SMILES
CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Isomeric SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Solubility ( literature )

DMSO, Methanol, Ethanol. Unstable in Methanol.

Compound Classification
  • Cyclodecane
  • Antitumor agent.
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

A antineoplastic drug. A tool in Microtubuli research

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Plant-derived
Research field: Cancer
Angiogenesis related
Research field: Signal Transduction
Signal to sort
P

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Paclitaxel__Taxol_.gif
Paclitaxel__Taxol_.gif

Mithramycin A

Mithramycin A
Molecular Formula
C52H76O24
M.W.
1 085.00
CAS number
18378-89-7
MSDS
Source
Streptomyces argillaceus
Fermentek product Code
MTA-001
Brand/grade
For research
Appearance
Yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
175°C-185°C
Solubility test
Clear yellowish solution at 100mg/ml DMSO
Names and identifiers

Synonyms:

  • Mithramycin
  • Plicamycin
  • Aureolic acid

RTECS: PZ2800000

EU number
634-048-4
Description

Oligosaccharide antibiotic, a RNA synthesis inhibitor.

InChl Key
CFCUWKMKBJTWLW-BKHRDMLASA-N
Canonical SMILES
CC1C(C(CC(O1)OC2CC(OC(C2O)C)OC3=CC4=CC5=C(C(=O)C(C(C5)C(C(=O)C(C(C)O)O)OC)OC6CC(C(C(O6)C)O)OC7CC(C(C(O7)C)O)OC8CC(C(C(O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O
Isomeric SMILES
C[C@@H]1[C@H]([C@@H](C[C@@H](O1)O[C@@H]2C[C@@H](O[C@@H]([C@H]2O)C)OC3=CC4=CC5=C(C(=O)[C@H]([C@@H](C5)[C@@H](C(=O)[C@H]([C@@H](C)O)O)OC)O[C@H]6C[C@H]([C@@H]([C@H](O6)C)O)O[C@H]7C[C@H]([C@H]([C@H](O7)C)O)O[C@H]8C[C@]([C@@H]([C@H](O8)C)O)(C)O)C(=C4C(=C3C)O)O)O)O
Solubility ( literature )

DMSO, Methanol, Ethanol

Compound Classification

Anthracycline Pentaglycosidic antibiotic.

RNA synthesis inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

DNA binding fluorescent dye. Until 2000 it was used to reduce high levels of plasma calcium. Used as an antineoplastic agent in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not dangerous goods
Title
Deleted CAS numbers
Value
1395-17-1; 1403-98-1; 12708-66-6; 12708-67-7; 23973-19-5; 97666-60-9; 219612-19-8; 744999-90-4; 807260-73-7; 826336-23-6; 899900-19-7; 1195235-16-5
Title
CN code
Value
29419000
Title
toxicity by RTECS
Value
LD50 oral mouse 500 mg/kg
Title
toxicity by RTECS
Value
TDLo oral human 50 ug/kg* 5D
Title
EPA USA status
Value
EPA GENETOX PROGRAM 1988, Positive: CHO gene mutation
Fermentek Product Category
Antibiotics
Research field: Cancer
Angiogenesis related
Anti Viral
Cancer Related Compounds
DNA replication inhibitors
Immunomodulators
Signal to sort
M

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Price
$1.00
Mithramycin_A.gif
Mithramycin_A.gif

Cytochalasin E

Cytochalasin E
Molecular Formula
C28H33NO7
M.W.
495.56
CAS number
36011-19-5
MSDS
Source
Aspergillus clavatus
Fermentek product Code
CYE-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
205°C-220°C
Solubility test
Clear colorless solution at 50mg/ml DMSO
Names and identifiers

 

HSDB 3548

RTECS HA5360000

 

EU number
252-835-7
Description

Inhibitor of actin polymerization in blood platelets. It does not inhibit glucose transport.

InChl Key
LAJXCUNOQSHRJO-ZYGJITOWSA-N
Canonical SMILES
CC1CC=CC2C3C(O3)(C(C4C2(C(=O)NC4CC5=CC=CC=C5)OC(=O)OC=CC(C1=O)(C)O)C)C
Isomeric SMILES
C[C@H]1C/C=C/[C@H]2[C@H]3[C@](O3)([C@H]([C@@H]4[C@]2(C(=O)N[C@H]4CC5=CC=CC=C5)OC(=O)O/C=C/[C@@](C1=O)(C)O)C)C
Solubility ( literature )

DMSO, ethyl acetate, ethanol, dichloromethane

Compound Classification

Macrolide indol mycotoxin

Cytochalasin

Actin polymerization inhibitor

Antiangiogenic

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Retest time
3 Years
Ingredient type
Fermentek product
Available since
Title
since
Value
1999
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Cytochalasins
Angiogenesis related
Signal to sort
C
Cytochalasin_E.gif
Cytochalasin_E.gif

Castanospermine

Castanospermine
Molecular Formula
C8H15NO4
M.W.
189.21
CAS number
79831-76-8
Source
Castanospermum australe (plant extract)
Fermentek product Code
CAS-001
Brand/grade
For research
Appearance
White to off-white solid.
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
202°C-215°C
Names and identifiers

Synonyms:

  • 1,6,7,8-Tetrahydroxyoctahydroindolizine
EU number
616-743-4
Description

Alkaloid extracted from an australian legume. Potent inhibitor of α- and β-glucosidase activity in fibroblast extracts; inhibits the glycoprotein processing cycle. Exhibits antiviral properties. Inhibits angiogenesis.

InChl Key
JDVVGAQPNNXQDW-TVNFTVLESA-N
Canonical SMILES
C1CN2CC(C(C(C2C1O)O)O)O
Isomeric SMILES
C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O
Solubility ( literature )

Soluble in water.

Compound Classification

Indolizidine alkaloid

Glycosidase Inhibitor

Angiogenesis inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Potent inhibitor of α- and β-glucosidases. 
Inhibits HIV infectivity. 
Inhibits angiogenesis. 
Inhibits thyroglobulin secretion. 
Antitumor activty. 
Inhibits protein glycosylation.

Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Plant-derived
Angiogenesis related
Anti Viral
Signal to sort
C

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Price
$1.00
Castanospermine.gif
Castanospermine.gif

Borrelidin

Borrelidin
Molecular Formula
C28H43NO6
M.W.
489.64
CAS number
7184-60-3
MSDS
Source
Streptomyces sp.
Fermentek product Code
BOR-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
106°C-114°C
Solubility test
Clear colorless solution at 10 mg/ml of Methanol or DMSO or Chloroform
Names and identifiers
  • Treponemycin
  • Cyclopentanecarboxylic acid
  • 2-[(4E,6E)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid
  • RTECS ED8750000
EU number
811-923-0
Description

Borrelidin is a macrolide-polyketide antibiotic displaying anti-viral, anti-bacterial, anti-malarial, and anti-angiogenic properties.

InChl Key
OJCKRNPLOZHAOU-UGKRXNSESA-N
Canonical SMILES
CC1CC(CC(C(C(=CC=CCC(OC(=O)CC(C(C1)C)O)C2CCCC2C(=O)O)C#N)O)C)C
Isomeric SMILES
C[C@H]1C[C@H](C[C@@H]([C@H](/C(=C\C=C\C[C@H](OC(=O)C[C@@H]([C@H](C1)C)O)[C@@H]2CCC[C@H]2C(=O)O)/C#N)O)C)C
Solubility ( literature )

Borrelidin is soluble in DMF, DMSO, Ethanol, Ethyl acetate, Methanol

Compound Classification
  • Cyclin-dependent kinase (CDK) inhibitor ;
  • Antiviral agent
  • Anti- Angiogenetic agent
  • Apoptosis inducer
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
2 Years
Applications

Borrelidin, a potent antifungal agent

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers
Value
1403-11-8; 97328-74-0
Title
Transport information
Value
Not hazardous for transport
Title
Inhibitor of:
Value
threonyl aminoacyl-tRNA synthetase; cyclin-dependent kinase (CDK).
Fermentek Product Category
Antibiotics
Enzyme-inhibitors
Research field: Cancer
Angiogenesis related
Apoptosis related
Protein synthesis inhibitors
Anti Protozoal
Anti Bacterial
Anti Viral
Cancer Related Compounds
Signal to sort
B

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Borrelidin.gif
Borrelidin.gif

Aureothricin

Aureothricin
Molecular Formula
C9H10N2O2S2
M.W.
242.30
CAS number
574-95-8
Source
Streptomyces luteosporeus
Fermentek product Code
AUR-001
Brand/grade
For research
Appearance
Yellow crystalline powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
280°C-285°C
Solubility test
Clear yellow solution at 1 mg/ml DMSO or DMF
Names and identifiers

IUPACK name:

N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)propanamide;

N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-propanamide;

Chemical names:

Aureothricin; Propionopyrrothine; Farcinicin

 

Chemical name
N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolopyrrol-6-yl)-propanamide
Description

 Aureothricin is a small-molecule antibiotic containing sulfur,  with many valuable antibacterial, antifungal and anti-angiogenetic properties. Chemically it is an analog of Thioluthin.

InChl Key
UGZYFXMSMFMTSM-UHFFFAOYSA-N
Canonical SMILES
CCC(=O)NC1=C2C(=CSS2)N(C1=O)C
Solubility ( literature )

Aureothricin is soluble in Dichloromethane, DMSO and DMF. Moderately soluble in low alcohols such as Methanol and Ethanol. It is more hydrophobic than thiolutin; practically insoluble in water.

Compound Classification
  • Dithiolopyrrolone
  • Pyrrolidinone antibiotic
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Retest time
3 Years
Applications

RNA polymerase inhibitor Angiogenesis inhibitor Inhibitor of tumour-cell induced angiogenesis in vivo. Antineoplastic properties. Antibacterial and antifungal properties.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Antibiotics
Research field: Cancer
Angiogenesis related
Apoptosis related
Signal to sort
A

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Price
$1.00
Aureothricin.gif
Aureothricin.gif
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