Aureothricin
Molecular Formula
C9H10N2O2S2
M.W.
242.30
CAS number
574-95-8
Source
Streptomyces luteosporeus
Fermentek product Code
AUR-001
Brand/grade
For research
Appearance
Yellow crystalline powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
280°C-285°C
Solubility test
Clear yellow solution at 1 mg/ml DMSO or DMF
Names and identifiers

IUPACK name:

N-(4-methyl-5-oxodithiolo[4,3-b]pyrrol-6-yl)propanamide;

N-(4,5-dihydro-4-methyl-5-oxo-1,2-dithiolo[4,3-b]pyrrol-6-yl)-propanamide;

Chemical names:

Aureothricin; Propionopyrrothine; Farcinicin

 

Chemical name
N-(4,5-Dihydro-4-methyl-5-oxo-1,2-dithiolopyrrol-6-yl)-propanamide
Description

 Aureothricin is a small-molecule antibiotic containing sulfur,  with many valuable antibacterial, antifungal and anti-angiogenetic properties. Chemically it is an analog of Thioluthin.

InChl Key
UGZYFXMSMFMTSM-UHFFFAOYSA-N
Canonical SMILES
CCC(=O)NC1=C2C(=CSS2)N(C1=O)C
Solubility ( literature )

Aureothricin is soluble in Dichloromethane, DMSO and DMF. Moderately soluble in low alcohols such as Methanol and Ethanol. It is more hydrophobic than thiolutin; practically insoluble in water.

Compound Classification
  • Dithiolopyrrolone
  • Pyrrolidinone antibiotic
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Retest time
3 Years
Applications

RNA polymerase inhibitor Angiogenesis inhibitor Inhibitor of tumour-cell induced angiogenesis in vivo. Antineoplastic properties. Antibacterial and antifungal properties.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Signal to sort
A