Castanospermine

Molecular Formula

C8H15NO4

M.W.

189.21

CAS number

79831-76-8

Details

Source

Castanospermum australe (plant extract)

Fermentek product Code

CAS-001

Brand/grade

For research

Specifications

Appearance

White to off-white solid.

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

202°C-215°C

Chemical identification

Names and identifiers

Synonyms:

1,6,7,8-Tetrahydroxyoctahydroindolizine

EU number

616-743-4

Description

Alkaloid extracted from an australian legume. Potent inhibitor of α- and β-glucosidase activity in fibroblast extracts; inhibits the glycoprotein processing cycle. Exhibits antiviral properties. Inhibits angiogenesis.

InChl Key

JDVVGAQPNNXQDW-TVNFTVLESA-N

Canonical SMILES

C1CN2CC(C(C(C2C1O)O)O)O

Isomeric SMILES

C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O

Further Information

Solubility ( literature )

Soluble in water.

Compound Classification

Indolizidine alkaloid

Glycosidase Inhibitor

Angiogenesis inhibitor

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Open carefully.

Other vendors may recommend higher temperatures for storage.

Retest time

3 Years

Applications

Potent inhibitor of α- and β-glucosidases.
Inhibits HIV infectivity.
Inhibits angiogenesis.
Inhibits thyroglobulin secretion.
Antitumor activty.
Inhibits protein glycosylation.

Disclaimer

Refer to MSDS for further safety and handling instructions.

Composition

Ingredient type

Fermentek product

Special Info

Available since

2012