Castanospermine
Molecular Formula
C8H15NO4
M.W.
189.21
CAS number
79831-76-8
Source
Castanospermum australe (plant extract)
Fermentek product Code
CAS-001
Brand/grade
For research
Appearance
White to off-white solid.
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
202°C-215°C
Names and identifiers

Synonyms:

  • 1,6,7,8-Tetrahydroxyoctahydroindolizine
EU number
616-743-4
Description

Alkaloid extracted from an australian legume. Potent inhibitor of α- and β-glucosidase activity in fibroblast extracts; inhibits the glycoprotein processing cycle. Exhibits antiviral properties. Inhibits angiogenesis.

InChl Key
JDVVGAQPNNXQDW-TVNFTVLESA-N
Canonical SMILES
C1CN2CC(C(C(C2C1O)O)O)O
Isomeric SMILES
C1CN2C[C@@H]([C@H]([C@@H]([C@H]2[C@H]1O)O)O)O
Solubility ( literature )

Soluble in water.

Compound Classification

Indolizidine alkaloid

Glycosidase Inhibitor

Angiogenesis inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Potent inhibitor of α- and β-glucosidases. 
Inhibits HIV infectivity. 
Inhibits angiogenesis. 
Inhibits thyroglobulin secretion. 
Antitumor activty. 
Inhibits protein glycosylation.

Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Signal to sort
C