Standard Solution Patulin
Details
Chemical identification
Patulin 100ppm in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system; Available in 1 ml or 5 ml vials.
Food-safety related products include natural toxins which may (but should NOT) occur in food-stuffs, standartized "injection-ready" solutions of toxins in commonly used solvents and the like.
The standard solutions serve as the quantitatively reliable samples of the toxic materials, obtained from tested samples of food by conventional extraction methods.
Highly purified solid toxins serve as starting materials for preparation of antibodies, which may be a part of bioassays etc.
Patulin 100ppm in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system; Available in 1 ml or 5 ml vials.
HT2 toxin, 100 ppm solution in Acetonitrile, grade: "HPLC Supra Gradient "(CAS #75-05-8) Ready for Injection into HPLC system; Available in 1 ml or 5 ml vials.
This product is used as a reference standard in quantitative analysis of food stuffs.
Systemic name: Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
RTECS: YD0050000
HT2 Toxin is a trichothecene group mycotoxin; naturally found in spoiled foods.
Dichloromethane, DMSO, Ethanol, Ethyl Acetate. Slightly soluble in petroleum ether; very slightly soluble in water.
Trichothecene mycotoxin
Synonyms
RTECS KB4725000
Gliotoxin is a fungal antibiotic mycotoxin with antiphagycytic and immunomodulatory activities.
Gliotoxin is an antibiotic that is toxic to higher animals as well as to animal and plant pathogens and that is produced by various fungi (as of the genera Gliocladium, Aspergillus, andPenicillium)
DMSO, Methanol, Ethanol, Ethyl acetate, Petrol-ether, Dichloromethane. Water insoluble
Chemical class:
Bioactivity class:
Gliotoxin blocks the thiol groups in the membranes . Gliotoxin induces apoptotsis in macrophages and thymocytes. Gliotoxin induces Ca2+ release from intact rat liver mitochondria.
Synonyms
RTECS: YD0160000
Fusarenon X is a trichothecene mycotoxin from various Fusarium strains
Dichloromethane, Chloroform, Ethyl Acetate, Ethanol, Methanol, water. Not soluble in N-Hexane, petrol ether.
RTECS: TZ8335000
IUPAC name: (2R,2'R)-2,2'-{[(5R,6S,7S,9S,16R,18S,19S)-19-amino-16,18-dihydroxy-5,9-dimethylicosane-6,7-diyl]bis[oxy(2-oxoethane-2,1-diyl)]}disuccinic acid
Structural analog of Fumonisin B1. Fumonisin B2 is more cytotoxic than Fumonisin B1.
Fumonisin B2 inhibits sphingosine acyl-transterase.
Methanol
sphingosine acyl-transterase inhibitor
Synonyms:
Macrofusine
Systematic name: 1,2,3-Propanetricarboxylic acid, 1,1'-(1-(12-amino-4,9,11-trihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl) ester
RTECS : TZ8350000
A carcinogenic mycotoxin.
An inhibitor of sphingosine biosynthesis
Slightly soluble in water. Soluble in Acetonitril. Insoluble in Chloroform, Petrol Ether, Hexane.
Chemical classification
Biological activities
Synonyms:
IUPAC Name : (2E,4E,6E,8E)-10-({(3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl}oxy)-10-oxo-2,4,6,8-decatetraenoic acid
RTECS : HE1750000
Antiamoebic. Inhibitor of angiogenesis.
Reproduction effector
DMSO, Methanol. alkaline aqueous solutions
Chemical classification:
Fatty acid antibiotic.
Classification by bio-activity
Antiprotozoal
Synonyms:
Systematic Name: 7(S),20(R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E)-diene-1,23-dione
Dihydrocytochalasin B is chemically derived from Cytochalasin B obtained natural from Drechslera dematoidea fungus.
Acetone, DMSO, 100% Ethanol, Methanol
Cytochalasins are used as tools in cytological research, and in in the field of actin polymerisation.
Cytokinesis inhibitor. Inducer of changes in cell morphology and motility. It disrupts actin structure and inhibits ability of serum growth factors to stimulate DNA synthesis in vitro. Does not inhibit sugar uptake. Active calcium transport inhibitor. Active in vivo.
Diacetoxyscirpenol (DAS) also known as Anguidine, is a mycotoxin belonging to 12,13-epoxytrichothecene group, produced by several Fusarium strains together with some other toxins such as T2 and HT2 toxins.
DAS inhibits initiation of protein synthesis, causing the death of intensively replicating cells. By the virtue of this effect, DAS possesses teratogenic and anti proliferatory properties. Consequently, DAS attracts interest as a potential cancer- drug.
Soluble in moderately polar solvents, such as chloroform, diethyl ether, ethyl acetate, and acetone
Diacetoxyscirpenol (Anguidine) and its derivates possess anticancer properties. Diacetoxyscirpenol (Anguidine) inhibits initiation of protein synthesis, resulting in the death of rapidly proliferating cells. Diacetoxyscirpenol (Anguidine) also has been shown to both potentiate and protect against the cytotoxic effects of other drugs. There were 14 clinical trials reported, all in the area of colorectal tumors and leukemia. No records found after 1985. Apoptosis inducement.