Mycotoxins are defined as naturally occurring substances produced by filamentous fungi (moulds) that arouse toxic response when introduced in low amounts to animals through a natural pathway. These fungi are referred to as “toxigenic” fungi. They grow naturally as a form of contaminants on some food crops, majorly cereals, nuts and fruit. Conventionally, toxigenic fungi which contaminate crops have been classified into two groups: “field” and “storage” fungi. Field fungi (such as Cladosporium, Fusarium and Alternaria spp.) get to plants during the developmental stage of the plant; while storage fungi (e.g., Aspergillus and Penicillium spp.) proliferate during the storage period.

Mycotoxins, which are low weight secondary metabolites, produce harmful substances called Mycotoxicoses in animals which invariably impact public health. The toxicity effects of Mycotoxins could be acute or chronic, or both. The most toxic of these, is Aflatoxins. Aflatoxins B1, B2, G1 and G2 are a critical concern. A low-level exposure to Aflatoxin for a long term has been associated with different liver diseases such as cancer, jaundice, cirrhosis and hepatis. Also, they are genotoxic (DNA-damaging) carcinogenic and immunosuppressants. Ochratoxin A is another type of mycotoxin that is teratogenic (reproductive), immunosuppressant, and had been proved to have connection with kidney diseases. Other toxigenic fungi are associated with protein synthesis inhibition, genotoxic, and immune dysfunction.

Fermentek is a global leader in the production of high-standard reference material for Mycotoxins for food safety analysis and research. The company offers more than 60 types of Mycotoxins manufactured from various different microorganisms, divided into nine known Mycotoxin families. These products are formulated into a powdered form or standard solutions with high purity characterized by their melting points, TLC & HPLC. 

mycotoxins

Chaetocin

Chaetocin
Molecular Formula
C30H28N6O6S4
M.W.
696.84
CAS number
28097-03-2
Source
From Chaetomium sp
Fermentek product Code
CHT-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 25 mg/ml DMSO
Names and identifiers

Synonyms

  • Chetocin
  • Chaetocin
  • (3S,3'S,5aR,5aR,10bR,10'bR,11aS,11'aS)-2,2',3,3',5a,5'a,6,6'-octahydro-3,3'-bis(hydroxymethyl)-2,2'-dimethyl-[10b,10'b(11H,11'H)-bi3,11a-epidithio-11aH-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole]-1,1',4,4'-tetrone

RTECS: FM3032000

EU number
636-696-3
Description

A fungal metabolite which inhibits G9a histone methyltransferase.

InChl Key
PZPPOCZWRGNKIR-PNVYSBBASA-N
Canonical SMILES
CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C
Isomeric SMILES
c12c(N[C@@H]3N4[C@@]5(C[C@@]23[C@@]23c6c(N[C@@H]2N2[C@@]7(C3)C(N([C@@](C2=O)(SS7)CO)C)=O)cccc6)C(N([C@@](CO)(C4=O)SS5)C)=O)cccc1
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers:
Value
31794-18-0
Title
Inhibitor of:
Value
G9a histone methyltransferase
Title
Transport information
Value
Not hazardous for transport
Title
Research Areas
Value
HIV
Signal to sort
C

Roquefortine C

Roquefortine C
Molecular Formula
C22H23N5O2
M.W.
389.50
CAS number
58735-64-1
Source
Penicillium roqueforti
Fermentek product Code
RQC-001
Brand/grade
For research
Appearance
White to slightly yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10 mg/ml Methanol or DMSO
Names and identifiers

Synonyms

  • Roquefortine
  • Roquefortin
  • roquefortine C
  • Rorifone

RTECS: UQ4730500

HSDB 7246

Description

Roquefortine C is a mycotoxin produced by various fungi, particularly species from the Penicillium genus. It was first isolated from a strain of Penicillium roqueforti, a species commercially used to make Roquefort, Danish Blue, Stilton and Gorgonzola cheeses.

InChl Key
SPWSUFUPTSJWNG-CXUHLZMHSA-N
Canonical SMILES
CC(C)(C=C)C12CC3C(=O)NC(=CC4=CN=CN4)C(=O)N3C1NC5=CC=CC=C25
Isomeric SMILES
CC(C)(C=C)C12CC3C(=O)N/C(=C/C4=CN=CN4)/C(=O)N3C1NC5=CC=CC=C25
Solubility ( literature )

Soluble in 100% ethanol, methanol (10 mg/ml), DMSO (10 mg/ml), DMF, and water (poor).

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings
Ingredient type
Fermentek product
Available since
Title
Transport Information
Value
Not Dangerous Goods
Title
toxicity by RTECS
Value
Rodent - mouse ; intraoeritoneal LD50 = 15 mg/kg; no other data
Signal to sort
R

Fumonisin B3

Fumonisin B3
Molecular Formula
C34H59NO14
M.W.
705.80
CAS number
1422359-85-0
MSDS
Source
Fusarium moniliforme
Fermentek product Code
FB3-001
Brand/grade
For research
Appearance
White to slight yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution 5 mg/ml Methanol
Names and identifiers
  • IUPAC Name:  2-[2-[(5R,6R,7S,9S,11R,18R,19S)-19-amino-6-(3,4-dicarboxybutanoyloxy)-11,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
  • RTECS  TZ8340000
EU number
812-040-3
Description

A carcinogenic mycotoxin. An inhibitor of sphingosine biosynthesis

InChl Key
CPCRJSQNWHCGOP-KUHXKYQKSA-N
Canonical SMILES
CCCCC(C)C(C(CC(C)CC(CCCCCCC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
Isomeric SMILES
CCCC[C@@H](C)[C@H]([C@H](C[C@@H](C)C[C@@H](CCCCCC[C@H]([C@H](C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
Solubility ( literature )

Slightly soluble in water. Soluble in Methanol, Acetonitril. Insoluble in Chloroform, Petrol Ether, Hexane.

Compound Classification
  • Isoflavonoid
  • Phytoestrogen.
  • Sphingosine acyl-transterase inhibitor
Storage, handling
Protect from light
Retest time
3 Years
Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Title
Additional safety info
Value
GHS Hazards, EU Regulation 1272/2008, US OSHA 1910.1200) Not hazardous
Title
deleted CAS number
Value
136379-59-4
Signal to sort
F

Standard Solution Ochratoxin A

Standard Solution Ochratoxin A
MSDS
Fermentek product Code
STD-024
Brand/grade
Analytical standard
Description

Ochratoxin A 10ppm in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system; Available in 1 ml or 5 ml vials.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Disclaimer
Refer to MSDS for further safety and handling instructions
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
10 µg/ml in Acetonitrile
Ingredient Other
Acetonitrile , HPLC grade (CAS #75-05-8)
Ingredient type
Fermentek product
Ingredient amount
to 100%
Available since

Standard Solution Aflatoxin B2

MSDS
Fermentek product Code
STD-004
Brand/grade
Analytical standard
Description

Aflatoxin B2, 0.5 μg in 1 ml Acetonitrile "HPLC-Gradient grade". Ready for Injection into HPLC system.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Disclaimer
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
0.5 µg/ml in Acetonitrile
Ingredient Other
Acetonitrile, grade: "HPLC Supra Gradient "(CAS #75-05-8)
Ingredient type
Fermentek product
Ingredient amount
To 100%
Amber-glass vial.

Standard Solution Aflatoxin M2

MSDS
Fermentek product Code
STD-008
Brand/grade
Analytical standard
Description

Aflatoxin M2, 0.5 µg/ml in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
0.5 μg/ml in Acetonitrile
Ingredient Other
Acetonitrile, HPLC-gradient grade
Ingredient type
Fermentek product
Ingredient amount
to 100%
Amber-glass vial.

Standard Solution Aflatoxin M1

MSDS
Fermentek product Code
STD-006
Brand/grade
Analytical standard
Description

Aflatoxin M1, 0.5 µg/ml in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Disclaimer
Refer to MSDS for further safety and handling instructions
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
0.5μg/ml in Acetonitrile
Ingredient Other
Acetonitril, HPLC grade
Ingredient type
Fermentek product
Ingredient amount
to 100%

Standard Solution Aflatoxin G2

MSDS
Fermentek product Code
STD-007
Brand/grade
Analytical standard
Description

Aflatoxin G2 , 0.5 µg/ml in Acetonitrile "HPLC-Gradient grade". Ready for Injection into HPLC system.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Disclaimer
Refer to MSDS for further safety and handling instructions
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
0.5μg/ml in Acetonitrile
Ingredient Other
Acetonitrile, HPLC grade, CAS#75-05-8
Ingredient type
Fermentek product
Ingredient amount
p.s.

Standard Solution Deoxynivalenol

Standard Solution Deoxynivalenol
MSDS
Fermentek product Code
STD-013
Brand/grade
Analytical standard
Description

Deoxynivalenol (DON) 100 ppm, in Acetonitrile, HPLC Supra Gradient grade. Available in 1 or 5 cc amber-glass vials.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
100 µg/ml in Acetonitrile
Ingredient Other
Acetonitrile, HPLC Supra Gradient grade Acetonitrile (CAS #75-05-8)
Ingredient type
Fermentek product
Ingredient amount
to 100%

Standard Solution Aflatoxin B1

MSDS
Fermentek product Code
STD-003
Brand/grade
Analytical standard
Description

Aflatoxin B1, 2 µg in 1 ml solution in Acetonitrile, grade: "HPLC Supra Gradient "(CAS #75-05-8)
Ready for Injection into HPLC system.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Applications

Only to be used as a reference standard in analytical laboratories.

Disclaimer
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Refer to MSDS for further safety and handling instructions.
Warnings

Corrosive

  • Skin corrosion, categories 1A, 1B, 1C
  • Serious eye damage, category 1
Ingredient Reference
Ingredient type
Fermentek product
Ingredient amount
2 µg/ml in Acetonitrile
Ingredient Other
Acetonitrile, grade: "HPLC Supra Gradient" (CAS #75-05-8)
Ingredient type
Fermentek product
Ingredient amount
to 100%
Amber-glass vial.