IUPAC name: 4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
Patulin: a cytostatic, antibacterial mycotoxin. It inhibits potassium uptake, activates the p38 kinase. Patulin is of some public health concern because of its potential carcinogenic properties, and because it has been found in commercial apple juice and other apple products. (L.B. Bullerman, in Encyclopedia of Food Sciences and Nutrition (Second Edition), 2003).
Patulin is also an immunosuppressive agent that inhibits multiple aspects of macrophage function. J.D. Groopman, T.W. Kensler, in Encyclopedia of Human Nutrition (Second Edition), 2005
Patulin is soluble in DMSO, Methanol, Ethanol, water
- Lactone Mycotoxin
- Cell signaling reagent;
- apopotosis inducer
Patulin was suggested as a remedy against common cold and reached clinical trials step in 1943 in Great Britain. However Patulin was found to be inefficient as such.(International Journal of Epidemiology 2004;33:243–246)