Roridin A

Molecular Formula

C29H40O9

M.W.

532.62

CAS number

14729-29-4

MSDS

Download

Details

Source

Myrothecium sp.

Fermentek product Code

ROA-001

Brand/grade

For research

Specifications

Appearance

White to faint yellow powder

Purity by HPLC

≥98% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Solubility test

Clear colorless to faint yellow solution at 10mg/ml of DMSO or Chloroform

Chemical identification

Names and identifiers

Synonyms:

Verrucarin A, 7'-deoxo-7'-(1-hydroxyethyl)-
Roridin A
Roridan A
Antibiotic 379X

IUPAC:

(1'R,3'R,8'R,12'S,13'R,17'R,18'E,20'Z,24'R,25'S)-12'-Hydroxy-17'-[(1R)-1-hydroxyethyl]-5',13',25'-trimethyl-11'H,22'H-spiro[oxirane-2,26'-[2,10,16,23]tetraoxatetracyclo[22.2.1.03,8.08,25]heptacosa ;[4,18,20]triene]-11',22'-dione

RTECS# VL0355000

EU number

238-783-8

Description

A type D trichothecene mycotoxin exhibiting anticancer properties

InChl Key

NSFWWJIQIKBZMJ-PAGWOCKZSA-N

Canonical SMILES

CC1CCOC(C=CC=CC(=O)OC2CC3C4(C2(C5(CCC(=CC5O3)C)COC(=O)C1O)C)CO4)C(C)O

Isomeric SMILES

C[C@@H]1CCO[C@H](/C=C/C=C\C(=O)O[C@@H]2C[C@@H]3[C@]4([C@]2([C@]5(CCC(=C[C@H]5O3)C)COC(=O)[C@H]1O)C)CO4)[C@@H](C)O

Further Information

Compound Classification

Type D Thrichthecene.

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Other vendors may recommend higher temperatures for storage.

Protect from moisture!

Retest time

3 Years

Applications

Roridin A and other Roridins and Verrucarins are produced by "The Black Mold", a common name for Stachybotrys family of molds that infect houses. Exposure to Roridin A can cause nasal irritation, abundance bodily fluid emission, and harm to the olfactory framework. Gastrointestinal exposure to Roridins can cause ulceration or bleeding from the large intestine, hypermotility, diarrhea. Long-term exposure to Roridins has been reported to cause cognitive disorders.

Roridin A from Fermentek is manufactured using a Myrothecium mold (which belongs to the Stachybotrys family). It is used as a sample to detect Black Mold infection in houses.

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Composition

Ingredient type

Fermentek product

Supply related information

Shipped at ambient temperature

Special Info

Available since