Ochratoxin

Ochratoxin A (OTA or OA) is produced by Aspergilus and Penicillium fungi. It affects the kidneys and causes both acute and chronic lesions. It is also genotoxic and affects the immune system.

Ochratoxin A is a known contaminant of cereals.  Recently Ochratoxin A was found to contaminate a wide range of other stored products and processed foods including coffee, beer, dried fruit, wine, cocoa and nuts.

The EU has recently proposed statutory limits for Ochratoxin A of 5 µg/kg in raw cereal grains including rice and buckwheat, 3 µg/kg for derived cereal products or for cereal grains for direct human consumption, and 10 µg/kg in dried vine fruits.

Analytical methods used are based on TLC, HPLC or ELISA.

Fermentek offers Ochratoxin A and Ochratoxin B.

 

Zearalenone

Zearalenone is a mycotoxin produced by a number of Fusarium and Gibberella species that infect wheat, barley, rice, maize, sorghum, and contaminate many other agricultural products. It can survive processing in consumer products including corn and corn products, breakfast cereals, corn beer, wheat flour, bread and walnuts, as well as animal feed products.

Zearalenone causes hyperestrogenism, abortion, stillbirth's oestrus, infertility and sterility in domestic animals. Zearalenone is genotoxic and causes severe hormonal effects. It is considered a human mutagen or carcinogen and may cause human cervical cancer.

Zearalenone was evaluated by JECFA (Joint FAO/WHO Expert Committee on Food Additives) which established a temporary TDI (Tolerable Daily Intake) of 0.2 µg/kg of body weight per day. Estimates of average dietary intakes for some ‘European’ consumers were of the order of 0.02 µg/kg of body weight per day suggesting a significant margin of safety based on current knowledge.

TLC methods have been used for Zearalenone analysis but are now superseded by HPLC with UV or fluorescence detection, GC/ECD, GC/MS and HPLC/MS.

 

Patulin

Patulin is produced by Penicillium, Aspergillus and Byssochlamys species growing on apples, pears, grapes and other fruit. The principal risk arises when contaminated fruit is used for the production of juices and other processed products. The most important threat of Patulin for humans is in apples and in apple juice, particularly that produced by direct pressing of apples.

Patulin causes nausea, vomiting, gastrointestinal hyperaemia, distension, haemorrhage, and ulceration. It has also been shown to be immunotoxic and neurotoxic.

Codex Committees focusing on Food Additives and Contaminants, have established limits for Patulin in apple juice and in apple juice ingredients.

The quality of fruit juice is controlled in some countries by setting a 'guideline' or 'recommended' maximum concentration agreed upon with the apple processing industry. This is commonly set at 50 µg/litre.

Patulin can be detected using TLC, but the usual method of analysis is by HPLC with UV detection.

 

Citrinin

Citrinin, produced by Penicillium fungi is associated with yellow rice fever in the Far East. Citrinin is found in rice, wheat, flour, barley, maize, rye, oats, peanuts and fruit, and can cause kidney and liver damage to humans as well as to animals. Other effects include vasodilation, constriction of the bronchi and increased muscular tone. Cereal samples can be screened by TLC or ELISA while quantitative results can be provided by HPLC.

 

Cyclopiazonic acid

Cyclopiazonic acid is produced by Penicillium and Aspergillus species. It has been detected at levels up to 10 mg/kg or higher in maize, millet, peanuts, pulses, cheese, ham, sausage, frankfurters, mixed feeds, hay, tomato, milk and other foods and feeds.

Cyclopiazonic acid appears to be toxic when present in high concentrations. It has been found to be a neurotoxin and to cause decreased weight gain, diarrhea, dehydration, depression, hyperaesthesia, hypokinesis, and convulsion in animals. Human ‘kodua poisoning’ in India from ingestion of contaminated millet seeds has been linked to cyclopiazonic acid.

A GC/MS method has been used for cyclopiazonic acid detection, while recently a HPLC/Mass Spectrometric method has been reported for the determination of cyclopiazonic acid in fungal cultures.

 

Additional mycotoxins

In addition to the Aflatoxins, Fumonisins, Ergots, Trichocothecenes and others mentioned above, there are additional mycotoxins that pose food safety threats. These include mycotoxins produced by Alternaria, Beauvericin, Citreoviridin, Moniliformin, Paxilline, Penicillic acid and Penitrem A.

 

 All of these mycotoxins are produced and marketed by Fermentek. 

Ochratoxin alpha

Ochratoxin alpha
Molecular Formula
C11H9ClO5
M.W.
256.64
CAS number
19165-63-0
Source
Aspergillus ochraceus
Fermentek product Code
OCL-001
Brand/grade
For research
Appearance
Off White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear slight yellow solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:

 

  • alpha-Ochratoxin
  • Ochratoxin alpha
  • 5-chloro-8-hydroxy-3,4-dihydro-3-methylisocoumarin-7-carboxylic acid

Chemical names:

IUPAC:

(3R)-5-Chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromene-7-carboxylic acid

RTECS#

EU number
Not on ECHA as on 11-2023
Chemical name
(3R)-5-Chloro-8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-isochromene-7-carboxylic acid
Description

Nontoxic metabolite of Ochratoxin A

InChl Key
OSFWJKYWJMZKSM-SCSAIBSYSA-N
Canonical SMILES
CC1CC2=C(C=C(C(=C2C(=O)O1)O)C(=O)O)Cl
Isomeric SMILES
C[C@@H]1CC2=C(C=C(C(=C2C(=O)O1)O)C(=O)O)Cl
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

OTalpha (OTα) formed by the cleavage of the peptidic bond in OTA is a major metabolite not only in animals and humans, but also in microorganisms and enzyme systems. It is considered as a nontoxic product.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Shipped at ambient temperature

Helvolic acid

Helvolic acid (Fumigacin)
Molecular Formula
C33H44O8
M.W.
568.70
CAS number
29400-42-8
Source
Cephalosporium caerulens
Fermentek product Code
HEV-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
210°C-215°C
Solubility test
Clear colorless solution at 10mg/ml of DMSO;
Clear colorless solution at 10mg/ml of EtOAc
Names and identifiers

Synonyms: Helvolic acid;   Fumigacin; 

Chemical names:

IUPAC:  (2Z)-2-[(4S,5S,6S,8S,9S,10R,13R,14S,16S)-6,16-diacetyloxy-4,8,10,14-tetramethyl-3,7-dioxo-5,6,9,11,12,13,15,16-octahydro-4H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid

RTECS#:   RC1370000

EU number
N.A.
Chemical name
Fumigacin
Description

Helvolic acid (Fumigacin). A naturally occurring steroidal antibiotic from Aspergillus and related fungi. Helvolic acid is a mycotoxin with antibacterial activity.

InChl Key
MDFZYGLOIJNNRM-OAJDADRGSA-N
Canonical SMILES
CC1C2C(C(=O)C3(C(C2(C=CC1=O)C)CCC4C3(CC(C4=C(CCC=C(C)C)C(=O)O)OC(=O)C)C)C)OC(=O)C
Isomeric SMILES
C[C@H]1[C@@H]2[C@@H](C(=O)[C@]3([C@H]([C@]2(C=CC1=O)C)CC[C@@H]\4[C@@]3(C[C@@H](/C4=C(/CCC=C(C)C)\C(=O)O)OC(=O)C)C)C)OC(=O)C
Solubility ( literature )

DMSO, Acetone, Chloroform

Compound Classification

Mycotoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers
Value
1403-63-0
Title
Transport information
Value
NDG
Title
Animal rawmat
Value
yes
Signal to sort
H

alpha Zearalanol

alpha Zearalanol
Molecular Formula
C18H26O5
M.W.
322.40
CAS number
26538-44-3
MSDS
Source
Semisynthetic
Fermentek product Code
ZAL-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
180°C-185°C
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:      Zeranol;    α-Zearalanol; 

Chemical names:   

IUPAC: 6-(6,10-Dihydroxyundecyl)-beta-resorcylic acid, mu-lactone;

RTECS#  DM2520000

EU number
247-769-0
Description

Alpha-Zearalanol is a minor analogue of the zearalenone family of mycotoxins.

InChl Key
DWTTZBARDOXEAM-TZMCWYRMSA-N
Canonical SMILES
CC1CCCC(CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Isomeric SMILES
C[C@@H]1CCC[C@@H](CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Compound Classification

Macrolide.

Mycotoxin - Zearalenone group

Fito-estrogen

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Phytoestrogen alpha-zearalanol  improves vascular function  in  ovariectomized  hyperhomocvsteinemic  rats. 

 

 

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Transport safety: Not Dangerous Goods; Not Regulated
Available since
Title
Transport information
Value
Not hazardous for transport
Title
Deleted CAS Registry Numbers
Value
5975-81-5 | 21307-30-2 | 24507-00-4 | 39487-91-7 | 40036-43-9
Signal to sort
A

beta Zearalanol

beta Zearalanol
Molecular Formula
C18H26O5
M.W.
322.40
CAS number
42422-68-4
MSDS
Source
Semisynthetic
Fermentek product Code
ZBL-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
151°C-159°C
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:          

  • estrogen P 1560
  • taleranol

Chemical names:

  • β- Zearalanol

IUPAC:                

  • (7S,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(14),15,17-trien-13-one

RTECS#  DM2540000

 

EU number
636-982-8
Chemical name
beta Zearalanol
Description

Beta-Zearalanol, also known as taleranol, is a minor analogue of the zearalenone family of resorcinyl macrocyclic lactones, produced by several species of Fusarium. Like the other zearalenones, Beta-zearalanol exhibits estrogenic activity in animals.

 

 
InChl Key
DWTTZBARDOXEAM-JSGCOSHPSA-N
Canonical SMILES
CC1CCCC(CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Isomeric SMILES
C[C@H]1CCC[C@H](CCCCCC2=CC(=CC(=C2C(=O)O1)O)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Title
Transport information
Value
Not hazardous for transport
Title
validations
Value
SCIFINDER formula,structure, CAS validated
Signal to sort
B

Enniatin A1

Enniatin A1
Molecular Formula
C35H61N3O9
M.W.
667.87
CAS number
4530-21-6
Source
Fusarium sp
Fermentek product Code
ENA-002
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of DMSO or Methanol
Names and identifiers

Synonyms:

Chemical names: Enniatin A1

IUPAC: 3S,6R,9S,12R,15S,18R)-3,9-bis[(2S)-butan-2-yl]-4,10,16-trimethyl-6,12,15,18-tetra(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

IUPAC, Biological notation: cyclo[N(Me)Ile-D-OVal-N(Me)Ile-D-OVal-N(Me)Val-D-OVal]

 
EU number
215-737-5
Description

Enniatin A1 has been found to induce apoptosis in cancer cells ...

InChl Key
OWUREPXBPJFMOK-CIRFPNLUSA-N
Canonical SMILES
CCC(C)C1C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N1C)C(C)C)C(C)C)C)C(C)C)C(C)CC)C)C(C)C
Isomeric SMILES
CC[C@H](C)[C@H]1C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N1C)C(C)C)[C@@H](C)CC)C)C(C)C)C(C)C)C)C(C)C
Compound Classification

Chemical Classification:

Cyclodepsipeptide

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since

Altenuene

Altenuene
Molecular Formula
C15H16O6
M.W.
292.28
CAS number
29752-43-0
MSDS
Source
Alternaria sp.
Fermentek product Code
ALT-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
185°C-190°C
Solubility test
Clear colorless solution at 5mg/ml of Acetone or Methanol
Names and identifiers

Synonyms:

Chemical names:

Systematic name: 6H-Dibenzo(b,d)pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2-alpha,3-beta,4a-beta)-(+-)-

IUPAC: (2S,3S,4aS)-2,3,7-Trihydroxy-9-methoxy-4a-methyl-2,3,4,4a-tetrahydro-6H-benzo[c]chromen-6-one                              

RTECS#  HP8758000

EU number
814-111-4
Description

Mycotoxin from Alternaria moulds.

InChl Key
MMHTXEATDNFMMY-WBIUFABUSA-N
Canonical SMILES
CC12CC(C(C=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O)O
Isomeric SMILES
C[C@]12C[C@@H]([C@H](C=C1C3=CC(=CC(=C3C(=O)O2)O)OC)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Title
Deleted CAS Numbers
Value
916665-00-4; 31273-73-1;
Title
CAS comments
Value
Two distinct compounds: 889101-41-1 (-)(-)Altenuene from alternaria and 29752-43-0
Signal to sort
A

Enniatin A

Enniatin A
Molecular Formula
C36H63N3O9
M.W.
681.90
CAS number
2503-13-1
Source
Fusarium sp.
Fermentek product Code
ENA-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
121°C-125°C
Solubility test
Clear colorless solution at 10mg/ml of Dichloromethane or Methanol
Names and identifiers

Synonyms:

Chemical names:  Fusafungine ;   Enniatin-A

IUPAC: (3S,9S,12R,15S,18R)-9,15-bis[(2S)-butan-2-yl]-3-[(2R)-butan-2-yl]-4,10,16-trimethyl-6,12,18-tri(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

A Fusarium produced depsipeptide ionophore

RTECS#  

Condensed IUPAC:  cyclo[N(Me)Ile-D-OVal-N(Me)Ile-DL-OVal-N(Me)aIle-D-OVal]

EU number
215-737-5
Description

Enniatin A is a least abundant commponent of the Enniatin-complex. It has been recently made available as a pure compound, thanks to the most advanced preparative HPLC methods.

InChl Key
TWHBYJSVDCWICV-BHZTXFQCSA-N
Canonical SMILES
CCC(C)C1C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N1C)C(C)C)C(C)CC)C)C(C)C)C(C)CC)C)C(C)C
Isomeric SMILES
CC[C@H](C)[C@H]1C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N1C)C(C)C)[C@@H](C)CC)C)C(C)C)[C@@H](C)CC)C)C(C)C
Solubility ( literature )

Soluble in ethanol, methanol, DMSO, DMF.

Compound Classification

Chemical classification:  Cyclic depsipeptide.

Biological classification:

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Natural enniatins occure as a mixture of several related analogs, known as "Enniatins", or "Enniatin complex"

Enniatins occure in nature in the mycelia of some Fusarium species. Being cyclic and hydrophopic molecules, enniatins are able to act as ionophores. More recently their effects on acyl-CoA cholesterol transferase, transporters and the selectivity of their antitumor action have received more focus. Enniatin has not previously been available for investigation.

 

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg III
Title
Deleted CAS Numbers
Value
2503-13-1; 4530-29-4
Signal to sort
E

beta Zearalenol

beta Zearalenol
Molecular Formula
C18H24O5
M.W.
320.38
CAS number
71030-11-0
Source
Semisynthetic
Fermentek product Code
ZLB-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥97% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
160°C-175°C
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:

  • Beta-trans-Zearalenol
  • Beta-Zearalenol

Chemical names:

 

IUPAC:

(2E,7S,11S)-7,15,17-trihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),2,14,16-tetraen-13-one

 

RTECS#  DM2570000

EU number
664-283-8
Description

β-Zearalenol is a mycotoxin produced by several species of Fusarium. 
β-Zearalenol exhibits pronounced estrogenic activity, like other zearalenones. 
Contamination of grains by Fusarium species, notably maize, gives rise to high levels of zearalenol and is regarded as an important food quality issue for both human and animal health. 

InChl Key
FPQFYIAXQDXNOR-PMRAARRBSA-N
Canonical SMILES
CC1CCCC(CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O)O
Isomeric SMILES
C[C@H]1CCC[C@H](CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Protect from light !
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Raw mat
Value
Not animal
Signal to sort
B

alpha Zearalenol

alpha Zearalenol
Molecular Formula
C18H24O5
M.W.
320.38
CAS number
36455-72-8
MSDS
Source
Semisynthetic
Fermentek product Code
ZLA-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
163°C-170°C
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:

  • Alpha-Zearalenol;
  • Trans-Zearalenol,
  • α-Zearalenol; 
  • a-Zearalenol

Chemical names:

  • Alpha-Zearalenol;

IUPAC:

(3S,7R,11E)-7,14,16-Trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one

RTECS#  DM2560000

EU number
828-728-1
Description

Alpha-Zearalenol is a synthetic derivative of the macrolactone mycotoxin zearalenone, which is also manufactured by Fermentek by the method of fungal fermentation.. Alpha-Zearalenol is estrogenically active and demonstrates induction of premature uterine growth, increase of nuclear estrogen receptor levels, and a five fold increase of ornithine decarboxylase level (ODC). The increase of ODC level was 20-fold more pronounced with Alpha-Zearalenol than zearalenone, and Alpha-Zearalenol demonstrated three times more potent estrogenic activity than zearalenone.

InChl Key
FPQFYIAXQDXNOR-QDKLYSGJSA-N
Canonical SMILES
CC1CCCC(CCCC=CC2=CC(=CC(=C2C(=O)O1)O)O)O
Isomeric SMILES
C[C@H]1CCC[C@@H](CCC/C=C/C2=CC(=CC(=C2C(=O)O1)O)O)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
NDG
Signal to sort
A

Enniatin B

Enniatin B
Molecular Formula
C33H57N3O9
M.W.
639.82
CAS number
917-13-5
Source
Fusarium sp.
Fermentek product Code
ENB-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
172°C-176°C
Solubility test
Clear colorless solution at 10mg/ml of Dichloromethane or Methanol
Names and identifiers

 

Synonyms:

Chemical names:

IUPAC:

(3S,6R,9S,12R,15S,18R)-4,10,16-trimethyl-3,6,9,12,15,18-hexa(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone

IUPAC Condensed name, as an oligopeptide
cyclo[N(Me)Val-D-OVal-N(Me)Val-D-OVal-N(Me)Val-D-OVal]

RTECS n.a.

Description

Enniatin B is the most studied of four major analogues of the enniatin complex.

InChl Key
MIZMDSVSLSIMSC-VYLWARHZSA-N
Canonical SMILES
CC(C)C1C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N(C(C(=O)OC(C(=O)N1C)C(C)C)C(C)C)C)C(C)C)C(C)C)C)C(C)C
Isomeric SMILES
CC(C)[C@H]1C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)O[C@@H](C(=O)N1C)C(C)C)C(C)C)C)C(C)C)C(C)C)C)C(C)C
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since