Standard Solution Ochratoxin B
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Ochratoxin B, 10 ppm in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system; Available in 1 ml or 5 ml vials.
Mycotoxins are defined as naturally occurring substances produced by filamentous fungi (moulds) that arouse toxic response when introduced in low amounts to animals through a natural pathway. These fungi are referred to as “toxigenic” fungi. They grow naturally as a form of contaminants on some food crops, majorly cereals, nuts and fruit. Conventionally, toxigenic fungi which contaminate crops have been classified into two groups: “field” and “storage” fungi. Field fungi (such as Cladosporium, Fusarium and Alternaria spp.) get to plants during the developmental stage of the plant; while storage fungi (e.g., Aspergillus and Penicillium spp.) proliferate during the storage period.
Mycotoxins, which are low weight secondary metabolites, produce harmful substances called Mycotoxicoses in animals which invariably impact public health. The toxicity effects of Mycotoxins could be acute or chronic, or both. The most toxic of these, is Aflatoxins. Aflatoxins B1, B2, G1 and G2 are a critical concern. A low-level exposure to Aflatoxin for a long term has been associated with different liver diseases such as cancer, jaundice, cirrhosis and hepatis. Also, they are genotoxic (DNA-damaging) carcinogenic and immunosuppressants. Ochratoxin A is another type of mycotoxin that is teratogenic (reproductive), immunosuppressant, and had been proved to have connection with kidney diseases. Other toxigenic fungi are associated with protein synthesis inhibition, genotoxic, and immune dysfunction.
Fermentek is a global leader in the production of high-standard reference material for Mycotoxins for food safety analysis and research. The company offers more than 60 types of Mycotoxins manufactured from various different microorganisms, divided into nine known Mycotoxin families. These products are formulated into a powdered form or standard solutions with high purity characterized by their melting points, TLC & HPLC.
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Ochratoxin B, 10 ppm in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system; Available in 1 ml or 5 ml vials.
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(2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol
RTECS#: N.A.
Hydrolyzed fumonisin B2 occurs in alkaline cooked foods such as masa and tortillas. It inhibits sphingosine acyltransferase more weakly than the intact Fumonisin B2.
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Hydrolyzed fumonisin B1 (aka aminopentol) is a mycotoxin which occurs naturaly together with fumonisin B1. It may be formed from fumonisin B1 by hydrolysis of the O-acyl bonds.
Product natural
IUPAC: (2E)-2-{[(2E)-2-({[(2S)-1-{[(3R,4S,7S,10S,11S)-14-Chloro-3-ethyl-11,15-dihydroxy-7-isopropenyl-3-methyl-10-(methylamino)-6,9-dioxo-2-oxa-5,8-diazabicyclo[10.3.1]hexadeca-1(16),12,14-trien-4-yl]carbony l}-2,5-dihydro-1H-pyrrol-2-yl]carbonyl}amino)-3-methyl-2-pentenoyl]amino}-2-butenedioic acid
RTECS# SY2593000
Cyclic hexapeptide antibiotic. Phomopsin A exhibits very strong inhibitory properties of microtubule assembly. It binds to tubulin at a site different from the colchicine binding site.
Soluble in Ethanol, Methanol, DMSO and DMF. Sparingly siluble in water. Not stable in watery solutions. (lit).
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IUPAC: (5aS,12S,14aS)-9-Methoxy-12-(2-methyl-1-propen-1-yl)-1,2,3,5a,6,11,12,14a-octahydro-5H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-b]indole-5,14-dione
RTECS# UY8709670
Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognized Fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
Soluble in Ethanol, Methanol, DMF, DMSO Chloroform.
Negligible solubility ( 35 mg in 1 liter water @25°C) has been reported.
Breast cancer resistance protein inhibitor
Mammalian cell cycle inhibitors
Synonyms: Helvolic acid; Fumigacin;
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IUPAC: (2Z)-2-[(4S,5S,6S,8S,9S,10R,13R,14S,16S)-6,16-diacetyloxy-4,8,10,14-tetramethyl-3,7-dioxo-5,6,9,11,12,13,15,16-octahydro-4H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid
RTECS#: RC1370000
Helvolic acid (Fumigacin). A naturally occurring steroidal antibiotic from Aspergillus and related fungi. Helvolic acid is a mycotoxin with antibacterial activity.
DMSO, Acetone, Chloroform
Mycotoxin
Synonyms: Zeranol; α-Zearalanol;
Chemical names:
IUPAC: 6-(6,10-Dihydroxyundecyl)-beta-resorcylic acid, mu-lactone;
RTECS# DM2520000
Alpha-Zearalanol is a minor analogue of the zearalenone family of mycotoxins.
Macrolide.
Mycotoxin - Zearalenone group
Fito-estrogen
Phytoestrogen alpha-zearalanol improves vascular function in ovariectomized hyperhomocvsteinemic rats.
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RTECS# DM2540000
Beta-Zearalanol, also known as taleranol, is a minor analogue of the zearalenone family of resorcinyl macrocyclic lactones, produced by several species of Fusarium. Like the other zearalenones, Beta-zearalanol exhibits estrogenic activity in animals.
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RTECS# : BC9625200
Altertoxin-1, a natural mycotoxin from Alternaria fungi, an important contaminant in cereals, vegetables.
Altertoxin I (and other altertoxins) inhibit the HIV replication.
Synonyms: Zearalanone; (S)-Zearalanone; Zanone
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IUPAC: (11S)-15,17-dihydroxy-11-methyl-12-oxabicyclo[12.4.0]octadeca-1(18),14,16-triene-7,13-dione
RTECS# DM2530000
Zearalanone is a minor component of the zearalenone complex produced by several species of Fusarium. Like the more abundant analogues, zearalanone causes estrogenic effects in domestic livestock. Zearalanone is a metabolite of α-zearalanol, a commercially available growth promotant in animals, and is a useful standard for detection of zearanol-contaminated products and Fusarium-contaminated grains.
Soluble in ethanol, methanol, DMF or DMSO.
Soluble scarcely in water.