Bongkrekic acid (as solution)
Details
Specifications
Chemical identification
Synonyms:
- Bongkrekic Acid
- Flavotoxin A
Chemical names:
IUPAC:
- (6R,17S)-20-(carboxymethyl)-6-methoxy-2,5,17-trimethyldocosa-2,4,8,10,14,18,20-heptaenedioic acid
RTECS
Supplied as 1mg/ml solution dissolved in 0.01M Tris buffer pH 7.5.
Further Information
- Solubility in Water: ~ 1 mg/ml
- Solubility Notes: ~100 mg/ml in DMSO
- Chemical classification:
- Polyunsaturated tricarboxylic acid
Bioactivity:
- Glutathione transferase inhibitor
- ATP/ADP translocase inhibitor
Bongcrekic acid is an inhibitor of adenine nucleotide translocator, which inhibits apoptosis, and is thus an important tool for the mechanistic investigation of apoptosis.