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Puromycin dihydrochloride animal free

Molecular Formula

C22H29N7O5·(HCl)2

M.W.

471.52

CAS number

58-58-2

MSDS

Download

Details

Source

Streptomyces alboniger

Fermentek product Code

PUR-002

Brand/grade

For research

Specifications

Appearance

White to Off-White powder

Purity by HPLC

≥98% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

≥160°C (dec.)

Solubility test

Clear, slightly brown colorless solution at 50mg/ml of Water

Chemical identification

Names and identifiers

Synonyms:

Stylomycin
Achromycin

Chemical names:

IUAPC name: 3'-deoxy-N,N-dimethyl-3'-[(O-methyl-L-tyrosyl)amino]adenosine dihydrochloride

RTECS# AU7355000

EU number

200-388-3

Chemical name

Adenosine, 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, hydrochloride (1:2)

Description

This version of Puromycin has been prepared without using animal raw materials.
Puromycin is a protein synthesis inhibitor. It causes premature chain termination.

InChl Key

C22H29N7O5·(HCl)2

Canonical SMILES

CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O

Isomeric SMILES

CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O.Cl.Cl

Further Information

Compound Classification

Nucleoside antibiotic.
Protein synthesis inhibitor

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Protect from moisture

Protect from light !

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Other vendors may recommend higher temperatures for storage.

Retest time

3 Years

Applications

Puromycin is an antibiotic used for selecting mammalian cell lines, which have been transformed by vectors that express puromycin-N-acetyl-transferase. Puromycin is also a Antineoplastic agent. Puromycin possesses antoprotozoal activities (against Trypanozoma)

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Warnings

No animal ingredients

NotGMO

Product natural

Composition

Ingredient type

Fermentek product

Supply related information

Shipped at ambient temperature

Shipped in PP / PE bottle.

Antib-29419000

Special Info

Available since

2018

Other Fields

Title

EC safety - REACH; preregistered ; ANNEX III

Value

suspected : carcinogen, mutagen, toxic for reproduction

Fermentek Product Category

Antibiotics

Apoptosis related

Anti Bacterial

Read more about Puromycin dihydrochloride animal free

Signal to sort

Wilforlide A

Molecular Formula

C30H46O3

M.W.

454.68

CAS number

84104-71-2

Details

Source

Tripterygium wilfordii

Fermentek product Code

WIL-001

Brand/grade

For research

Specifications

Appearance

White powder

Purity by HPLC

≥98% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

315°C-321°C

Solubility test

Clear colorless solution at 10mg/ml of Methanol

Chemical identification

Names and identifiers

Synonyms:

Wilforlide A
Regelide
Abruslactone A

Chemical names:

(2S,5S,5aR,7aS,7bR,9aR,11S,13aR,13bR,15bS)-11-hydroxy-2,5a,7a,7b,10,10,13a-heptamethyl-1,5,5a,6,7,7a,7b,8,9,9a,10,11,12,13,13a,13b,14,15b-octadecahydro-2,5-methanochryseno[2,1-c]oxepin-3(2H)-one

Synonym: Wilforlide A; Regelide; Abruslactone A

IUPAC: (3β,22α)-3-Hydroxy-22,29-epoxyolean-12-en-29-one

RTECS#

EU number

683-224-7

InChl Key

HHQJBWYXBWOFJY-YLXTXNMFSA-N

Canonical SMILES

CC1(C2CCC3(C(C2(CCC1O)C)CC=C4C3(CCC5(C4CC6(CC5OC6=O)C)C)C)C)C

Isomeric SMILES

C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4C[C@]6(C[C@@H]5OC6=O)C)C)C)C)(C)C)O

Further Information

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Other vendors may recommend higher temperatures for storage.

Retest time

3 Years

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Warnings

No animal ingredients

NotGMO

Product natural

Health-Hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Irritating

Mutagene

Warning or harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Corrosive

Skin corrosion, categories 1A, 1B, 1C
Serious eye damage, category 1

Flammable

Composition

Ingredient type

Fermentek product

Supply related information

Shipped at ambient temperature

Shipped in PP / PE bottle.

Special Info

Available since

2019

Other Fields

Title

lit1

Value

Appearance: Solid powder Purity: >98% (or refer to the Certificate of Analysis) Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Custo

Title

lit2

Value

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Solubility: Soluble in DMSO Shelf Life: >3 years if stored properly Drug Formulation: This drug may be formulated in DMSO Stock Solution S

Fermentek Product Category

Plant-derived

Read more about Wilforlide A

Signal to sort

Brefeldin A

Molecular Formula

C16H24O4

M.W.

280.36

CAS number

20350-15-6

Details

Source

Eupenicillium brefeldianum

Fermentek product Code

BRF-001

Brand/grade

For research

Specifications

Appearance

White powder

Purity by HPLC

≥98% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

198°C-215°C

Solubility test

Clear colorless solution at 10 mg/ml Methanol

Chemical identification

Names and identifiers

Synonyms:

Nectrolide;
Synergisidin;
Cyanaein;
Ascotoxin
Cyanein
Decumbin
Brefeldin A

EC# : 606-528-3

Systematic name:

(1R,2E,6S,10E,11aS,13S,14aR)-1,13-Dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one

RTECS: GY8410000

EU number

606-528-3

Description

Brefeldin A is a macrocyclic lactone from fungal source, exhibiting a wide range of antibiotic activity.

InChl Key

KQNZDYYTLMIZCT-HHMYAMTESA-N

Canonical SMILES

CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O

Isomeric SMILES

C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C\C(=O)O1)O)O

Further Information

Solubility ( literature )

Methanol, Ethanol, Dichloromethane, DMSO, acetone or ethyl acetate

Compound Classification

Macrocyclic lactone antibiotic.
Antifungal
Antiviral
Protein Synthesis Inhibitor

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Other vendors may recommend higher temperatures for storage.

Retest time

3 Years

Applications

Inhibitor of protein translocation from endoplasmic reticulum (ER) to the Golgi apparatus.
Inhibitor of intracellular protein transport and protein secretionA macrolide isolated from Penicillium brefeldianum. It affects the vesticular transport of the Golgi apparatus and induces DNA fragmentation which leads to apoptosis.

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Warnings

No animal ingredients