NotAnimal

No animal ingredients

Puromycin dihydrochloride animal free

Puromycin dihydrochloride animal free
Molecular Formula
C22H29N7O5·(HCl)2
M.W.
471.52
CAS number
58-58-2
MSDS
Source
Streptomyces alboniger
Fermentek product Code
PUR-002
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
≥160°C (dec.)
Solubility test
Clear, slightly brown colorless solution at 50mg/ml of Water
Names and identifiers

Synonyms: 

  • Stylomycin
  • Achromycin

Chemical names:

IUAPC name: 3'-deoxy-N,N-dimethyl-3'-[(O-methyl-L-tyrosyl)amino]adenosine dihydrochloride

RTECS#  AU7355000

EU number
200-388-3
Chemical name
Adenosine, 3'-​[[(2S)​-​2-​amino-​3-​(4-​methoxyphenyl)​-​1-​oxopropyl]​amino]​-​3'-​deoxy-​N,​N-​dimethyl-​, hydrochloride (1:2)
Description
  • This version of Puromycin has been prepared without using animal raw materials.
  • Puromycin is a protein synthesis inhibitor. It causes premature chain termination.
InChl Key
C22H29N7O5·(HCl)2
Canonical SMILES
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O
Isomeric SMILES
CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O.Cl.Cl
Compound Classification
  • Nucleoside antibiotic.
  • Protein synthesis inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Protect from light !
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Other vendors may recommend higher temperatures for storage.
Applications

Puromycin is an antibiotic used for selecting mammalian cell lines, which have been transformed by vectors that express puromycin-N-acetyl-transferase. Puromycin is also a Antineoplastic agent. Puromycin possesses antoprotozoal activities (against Trypanozoma)

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings

NotAnimal

No animal ingredients

NotGMO

Product natural

Ingredient type
Fermentek product
Shipped at ambient temperature
Shipped in PP / PE bottle.
Antib-29419000
Available since
Title
EC safety - REACH; preregistered ; ANNEX III
Value
suspected : carcinogen, mutagen, toxic for reproduction
Fermentek Product Category
Signal to sort
P

Wilforlide A

Wilforlide A
Molecular Formula
C30H46O3
M.W.
454.68
CAS number
84104-71-2
Source
Tripterygium wilfordii
Fermentek product Code
WIL-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
315°C-321°C
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:

  • Wilforlide A
  • Regelide
  • Abruslactone A

Chemical names:

(2S,5S,5aR,7aS,7bR,9aR,11S,13aR,13bR,15bS)-11-hydroxy-2,5a,7a,7b,10,10,13a-heptamethyl-1,5,5a,6,7,7a,7b,8,9,9a,10,11,12,13,13a,13b,14,15b-octadecahydro-2,5-methanochryseno[2,1-c]oxepin-3(2H)-one

Synonym: Wilforlide A; Regelide; Abruslactone A

IUPAC: (3β,22α)-3-Hydroxy-22,29-epoxyolean-12-en-29-one 

RTECS#

EU number
683-224-7
InChl Key
HHQJBWYXBWOFJY-YLXTXNMFSA-N
Canonical SMILES
CC1(C2CCC3(C(C2(CCC1O)C)CC=C4C3(CCC5(C4CC6(CC5OC6=O)C)C)C)C)C
Isomeric SMILES
C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4C[C@]6(C[C@@H]5OC6=O)C)C)C)C)(C)C)O
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings

NotAnimal

No animal ingredients

NotGMO

Product natural

Health-Hazard

  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Warning or harmful

  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    • Respiratory tract irritation
    • Narcotic effects

Corrosive

  • Skin corrosion, categories 1A, 1B, 1C
  • Serious eye damage, category 1
Ingredient type
Fermentek product
Shipped at ambient temperature
Shipped in PP / PE bottle.
Available since
Title
lit1
Value
Appearance: Solid powder Purity: >98% (or refer to the Certificate of Analysis) Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Custo
Title
lit2
Value
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Solubility: Soluble in DMSO Shelf Life: >3 years if stored properly Drug Formulation: This drug may be formulated in DMSO Stock Solution S
Fermentek Product Category
Signal to sort
W

Brefeldin A

Brefeldin A
Molecular Formula
C16H24O4
M.W.
280.36
CAS number
20350-15-6
Source
Eupenicillium brefeldianum
Fermentek product Code
BRF-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
198°C-215°C
Solubility test
Clear colorless solution at 10 mg/ml Methanol
Names and identifiers

Synonyms:

  •         Nectrolide;
  •         Synergisidin;
  •         Cyanaein;
  •         Ascotoxin
  •         Cyanein
  •         Decumbin
  •         Brefeldin A

EC# :     606-528-3

 Systematic name:

(1R,2E,6S,10E,11aS,13S,14aR)-1,13-Dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one

RTECS: GY8410000

EU number
606-528-3
Description

Brefeldin A is a macrocyclic lactone from fungal source, exhibiting a wide range of antibiotic activity.

InChl Key
KQNZDYYTLMIZCT-HHMYAMTESA-N
Canonical SMILES
CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O
Isomeric SMILES
C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C\C(=O)O1)O)O
Solubility ( literature )

Methanol, Ethanol, Dichloromethane, DMSO, acetone or ethyl acetate

Compound Classification
  • Macrocyclic lactone antibiotic.
  • Antifungal
  • Antiviral
  • Protein Synthesis Inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Applications

Inhibitor of protein translocation from endoplasmic reticulum (ER) to the Golgi apparatus.
Inhibitor of intracellular protein transport and protein secretionA macrolide isolated from Penicillium brefeldianum. It affects the vesticular transport of the Golgi apparatus and induces DNA fragmentation which leads to apoptosis.

 

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings

NotAnimal

No animal ingredients

NotGMO

Product natural

Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Pg III
Title
sig
Value
203729
Title
TSE
Value
F
Signal to sort
B