Epigallocatechin Gallate

Epigallocatechin Gallate
Molecular Formula
C22H18O11
M.W.
458.40
CAS number
989-51-5
Source
Extracted from Green Tea (leaves)
Fermentek product Code
EPG-001
Brand/grade
For research
Appearance
White to Beige lyophilized powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10 mg/ml H2O
Names and identifiers

RTECS KB5200000

EU number
619-381-5
Chemical name
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Description

Epigallocatechin is a phenolic antioxidant found in a number of plants such as green and black tea.
Epigallocatechin inhibits cellular oxidation and prevents free radical damage to cells. 

 

InChl Key
WMBWREPUVVBILR-WIYYLYMNSA-N
Canonical SMILES
C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Isomeric SMILES
C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Compound Classification

- Antioxidant

- Potential cancer-preventive agent. 

- Inhibitor of Telomerase

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from light !
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Epigallocatechin is being studied as a potential cancer chemo preventive agent.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Plant-derived
Enzyme-inhibitors
Research field: Cancer
Protein kinase related
Research field: Signal Transduction
Signal to sort
E

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Price
$1.00
Epigallocatechin_gallate__EGCG_.gif
Epigallocatechin_gallate__EGCG_.gif

Thapsigargin

Thapsigargin
Molecular Formula
C34H50O12
M.W.
650.75
CAS number
67526-95-8
MSDS
Source
Thapsia garganica
Fermentek product Code
THP-001
Brand/grade
For research
Appearance
White to faint yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml Acetonitrile
Names and identifiers

Synonyms: octanoic acid {3S-[3alpha,3abeta,4alpha,6beta,6abeta,7beta,8alpha(Z),9balpha]}-6-(acetoxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy)-azuleno[4,5-b]furan-7-yl ester

RTECS  RH0352700 

EU number
614-076-3
Description

Thapsigargin is a cell-permeable, tumor promoting sesquiterpene lactone. A tight-binding inhibitor of intracellular calcium (SERCA) pumps (sarco/endoplasmic reticulum Ca2+ ATPase). Chemically it is classified as a sesquiterpene lactone antibiotic.

A study from the University of Nottingham showed promising results for its use against Covid-19 and other coronavirus.

 

InChl Key
IXFPJGBNCFXKPI-FSIHEZPISA-N
Canonical SMILES
CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O
Isomeric SMILES
CCCCCCCC(=O)O[C@H]1[C@H]2C(=C([C@@H]1OC(=O)/C(=C\C)/C)C)[C@H]3[C@]([C@H](C[C@]2(C)OC(=O)C)OC(=O)CCC)([C@](C(=O)O3)(C)O)O
Solubility ( literature )

DMSO, Acetonitril, Ethanol, Methanol, Dichloromethane

Compound Classification
  • Sesquiterpene lactone
  • SERCA inhibitor
  • Apoptosis related antibiotic
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Hygroscopic substance.
Protect from moisture
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Title
TSE category
Value
V
Fermentek Product Category
Plant-derived
Cytotoxic agents
Apoptosis related
Anti Viral
Cancer Related Compounds
Anti Tumor agents
Signal to sort
T

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$1.00
Thapsigargin.gif
Thapsigargin.gif

Resveratrol

Resveratrol
Molecular Formula
C14H12O3
M.W.
228.20
CAS number
501-36-0
Source
Plant extract
Fermentek product Code
RES-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
250°C-263°C
Solubility test
Clear colorless solution at 20mg/ml Ethanol
Names and identifiers
  • trans-3,4',5-Trihydroxystilbene
  • RTECS CZ8987000
EU number
610-504-8
Description

Resveratrol is phytoestrogen with antitumor, antioxidant, antiplatelet, anti-inflammatory and antifungal effects.

InChl Key
LUKBXSAWLPMMSZ-OWOJBTEDSA-N
Canonical SMILES
C1=CC(=CC=C1C=CC2=CC(=CC(=C2)O)O)O
Isomeric SMILES
C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O
Solubility ( literature )

Resveratrol is soluble in Ethanol (at 5%), in DMSO (at 1.5%)

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Plant-derived
Signal to sort
R

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Price
$1.00
Resveratrol.gif
Resveratrol.gif

Parthenolide

Parthenolide
Molecular Formula
C15H20O3
M.W.
248.32
CAS number
20554-84-1
Source
Tanacetum parthenium
Fermentek product Code
PAR-001
Brand/grade
For research
Appearance
White crystalline solid.
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
112°C-118°C
Solubility test
Clear colorless solution at 50mg/ml Dichloromethane; Clear colorless solution at 50mg/ml DMSO
Names and identifiers

IUPAC name: (1aR,4E,7aS,10aS,10bS)-1a,5-Dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one

RTECS: LY4220000

EU number
692-532-0
Chemical name
Parthenolide
Description

Parthenolide is a sesquiterpene lactone and active principle of feverfew (Chrysanthemum parthenium)

InChl Key
KTEXNACQROZXEV-PVLRGYAZSA-N
Canonical SMILES
CC1=CCCC2(C(O2)C3C(CC1)C(=C)C(=O)O3)C
Isomeric SMILES
C/C/1=C\CC[C@@]2([C@H](O2)[C@@H]3[C@@H](CC1)C(=C)C(=O)O3)C
Solubility ( literature )

DMSO (100 mg/ml), Ethanol (20 mg/ml), Dichloromethane.

Compound Classification
  • sesquiterpene lactone

MAP kinase inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Other vendors may recommend +2 to +8°C storage.
Retest time
3 Years
Applications

Parthenolide has anti-inflammatory, antisecretory and spasmolytic activity. It Inhibits the release of various mediators. It inhibits activation of MAP kinase.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Plant-derived
Antibiotics
Research field: Cancer
Protein kinase related
Research field: Signal Transduction
Signal to sort
P

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Price
$1.00
Parthenolide.gif
Parthenolide.gif

Paclitaxel (Taxol)

Paclitaxel (Taxol)
Molecular Formula
C47H51NO14
M.W.
853.90
CAS number
33069-62-4
Source
Taxus brevifolia ( a plant extract)
Fermentek product Code
PAC-001
Brand/grade
For research
Appearance
White crystalline solid.
Purity by HPLC
≥ 98% ; refer to CoA for more data
Melting point
200°C to 220°C (decomposition)
Solubility test
Clear colorless solution at 50mg/ml of Methanol.
Names and identifiers

RTECS: DA8340700

EU number
608-826-9
Description

Paclitaxel (taxol) is an antineoplastic agent from a plant extract.

Paclitaxel  (taxol) stabilizes microtubules in their polymerized form thus leading to cell death

InChl Key
RCINICONZNJXQF-MZXODVADSA-N
Canonical SMILES
CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Isomeric SMILES
CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
Solubility ( literature )

DMSO, Methanol, Ethanol. Unstable in Methanol.

Compound Classification
  • Cyclodecane
  • Antitumor agent.
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

A antineoplastic drug. A tool in Microtubuli research

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Plant-derived
Research field: Cancer
Angiogenesis related
Research field: Signal Transduction
Signal to sort
P

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Price
$1.00
Paclitaxel__Taxol_.gif
Paclitaxel__Taxol_.gif

Hypericin

Hypericin
Molecular Formula
C30H16O8
M.W.
504.44
CAS number
548-04-9
Source
Hypericium perforatum (plant extract)
Fermentek product Code
HYP-001
Brand/grade
For research
Appearance
Blue – black powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear red solution at 10mg/ml DMSO
Names and identifiers
  • Cyclo-Werrol
EU number
208-941-0
Description

Natural antidepressant. Anti-retroviral agent. A protein kinaze-C inhibitor.

InChl Key
BTXNYTINYBABQR-UHFFFAOYSA-N
Canonical SMILES
CC1=CC(=C2C3=C1C4=C5C(=C(C=C4C)O)C(=O)C6=C(C=C(C7=C6C5=C3C8=C7C(=CC(=C8C2=O)O)O)O)O)O
Solubility ( literature )

Soluble in alkaline aqueous solutions. Soluble in organic bases such as pyridine (red fluorescent solutions) but not in other organic solvents

Compound Classification
  • Perylene analog.
  • Anthraquinone derivative
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Retest time
3 Years
Applications

Antidepressant. Apoptosis inducer. PKC inhibitor. Antiviral

Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient type
Fermentek product
Available since
Title
Deleted CAS numbers
Value
345224-62-6; 693273-27-7;935869-37-7
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Plant-derived
Research field: Cancer
Protein kinase related
Anti Viral
Cancer Related Compounds
Immunosupressors
Immunomodulators
Signal to sort
H

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$1.00
Hypericin.gif
Hypericin.gif

Genistein

Genistein
Molecular Formula
C15H10O5
M.W.
270.20
CAS number
446-72-0
Source
Soy bean (plant extract)
Fermentek product Code
GEN-001
Brand/grade
For research
Appearance
White solid.
Purity by HPLC
≥98% ; refer to CoA for more data
Melting point
295°C-300°C
Solubility test
Clear colorless solution at 50mg/ml DMSO
Names and identifiers

Synonyms: 4′,5,7-Trihydroxyisoflavone

RTECS: NR2392000

 

EU number
207-174-9
Description

Genistein: an isoflavone with anticancer, antiproliferation, and chemopreventive effects. Genistein induces cell differentiation. Genistein inhibits protein histidine kinase.

InChl Key
TZBJGXHYKVUXJN-UHFFFAOYSA-N
Canonical SMILES
C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
Solubility ( literature )

Genistein is soluble in DMSO, Ethanol.

Compound Classification

isoflavonoid

histidine kinase inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Plant-derived
Antibiotics
Research field: Cancer
Signal to sort
G

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Price
$1.00
Genistein.gif
Genistein.gif

Forskolin

Forskolin
Molecular Formula
C22H34O7
M.W.
410.50
CAS number
66575-29-9
MSDS
Source
Coleus forskohlii (plant extract)
Fermentek product Code
FOR-001
Brand/grade
For research
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
220°C-230°C
Solubility test
Clear colorless solution at 10mg/ml EtOAc
Names and identifiers

Synonyms :

Boforsin; Colforsin; Coleonol

RTECS QL6150000

EU number
266-410-9
Description

Forskolin is a labdane diterpene that is produced by Coleus forskohlii

InChl Key
OHCQJHSOBUTRHG-KGGHGJDLSA-N
Canonical SMILES
CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O
Isomeric SMILES
CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O
Solubility ( literature )

Forskolin is soluble in DMSO, Methanol, Ethanol, Dichloromethane, Forskolin may be dissolved in 2% ethanol in water, by dissolving it first in Ethanol and subsequently diluting this solution with water.

Compound Classification
  • diterpene antibiotic
  • vasodilator
Storage, handling
Room temperature or below. Light protection is recommended by other sources.
Retest time
3 Years
Applications
  • Bronchodilator agent,  Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
  • Cardiotonic agent: Agents that have a strengthening effect on the heart or that can increase cardiac output. 
  • Vasodilator agent: Agent   causing dilation of the blood vessels.
  • Forskolin activates Adenylate Cyclase, thus increasing the cyclic AMP intra-cellular concentration. Forskolin is commonly used to raise levels of cyclic AMP (cAMP) in the study and research of cell physiology. Forskolin has been mentioned as a possible weight loss aid, and as a mean to treat Glaucoma, as it may reduce the intraocular pressure. See also United States Patent Application 20100168014
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Plant-derived
Antibiotics
Vasodilator Agents
Signal to sort
F

Quote for

Price
$1.00
Forskolin.gif
Forskolin.gif

Cyclopamine

Cyclopamine
Molecular Formula
C27H41NO2
M.W.
411.62
CAS number
4449-51-8
Source
Veratrum californicim (plant extract)
Fermentek product Code
CLP-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
224°C-232°C
Solubility test
Clear colorless solution at 5mg/ml DMSO or Methanol
Names and identifiers

Synonyms: 11-deoxojervine

RTECS: GY0750000

EU number
628-058-8
Description

Cyclopamine is a natural steroidal jerveratrum alkaloide. Cyclopamine is named after its ability to cause cyclopia(holoprosencephaly) in unborn sheep.

InChl Key
QASFUMOKHFSJGL-LAFRSMQTSA-N
Canonical SMILES
CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1
Isomeric SMILES
C[C@H]1C[C@@H]2[C@H]([C@H]([C@]3(O2)CC[C@H]4[C@@H]5CC=C6C[C@H](CC[C@@]6([C@H]5CC4=C3C)C)O)C)NC1
Solubility ( literature )

Insoluble in water. Freely soluble in Chloroform, Dichloromethane.Fairly soluble in benzene, warm (50ºC-60ºC) ethanol (20 mg/mL ), DMSO (4 mg/ml) and DMF (10 mg/mL). May recrystallize from ethanolic solution in cold.

Compound Classification
  • Veratrum Alkaloid
  • Hh inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Retest time
3 Years
Applications

Known teratogen. Causes damage to embryos. Women who are or may be pregnant should avoid any contact with Cyclopamine

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Fermentek Product Category
Plant-derived
Signal to sort
C

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Price
$1.00
Cyclopamine.gif
Cyclopamine.gif

Chelerythrine chloride

Chelerythrine chloride
Molecular Formula
C21H18NO4∙Cl
M.W.
383.82
CAS number
3895-92-9
Source
Chelidonium majus
Fermentek product Code
CHE-001
Brand/grade
For research
Appearance
Yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
202°C-208°C
Solubility test
Clear yellowish solution at 5mg/ml Methanol
Names and identifiers

EINECS 223-444-9

1,2-Dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium chloride

Chelerythrine hydrochloride

EU number
223-444-9
Description

Chelerythrine: A benzophenanthridine alkaloid. A potent, selective, and cell-permeable PKC inhibitor.Chelerythrine is very closely related to sanguinarine. Unlike sanguinarine which is found in the green biomass of Chelidonium, Chelerythrine mainly occurs in its roots.

InChl Key
WEEFNMFMNMASJY-UHFFFAOYSA-M
Canonical SMILES
C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-]
Solubility ( literature )

Methanol, Water, DMSO

Compound Classification

Benzophenanthridine alkaloid

PKC inhibitor

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Retest time
3 Years
Ingredient type
Fermentek product
Available since
Title
Oral Toxicity Mouse
Value
No data.
Title
Transport safety information
Value
Not hazardous for transport
Fermentek Product Category
Plant-derived
Enzyme-inhibitors
Protein kinase related
Research field: Signal Transduction
Signal to sort
C

Quote for

Price
$1.00
Chelerythrine_Chloride.gif
Chelerythrine_Chloride.gif
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