- Clostomicin B1,
- lipiarmycin A3,
- tiacumicin B
IUPAC: [(2R,3S,4S,5S,6R)-6-[[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-(2-methylpropanoyloxy)oxan-2-yl]oxy-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo-1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy]-4-hydroxy-5-methoxy-2-methyloxan-3-yl] 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate
RTECS# Not available
Fidaxomicin is a narrow spectrum macrocyclic antibiotic, sourced from actinomycete Dactylosporangium aurantiacum. Fidaxomicin is non-systemic, meaning it is minimally absorbed into the bloodstream. This anti-bacterial agent selectively acts against pathogenic Clostridium difficile bacteria which may infect the colon, while causing minimal damage to the natural intestinal microbial flora.
Reportedly, Fidaxomicin is soluble in CHCl3(10 mg/ml), methanol(10 mg/ml), DMSO(1mg/ml); poor water solubility.