Virginiamycin M1
Molecular Formula
C28H35N3O7
M.W.
525.59
CAS number
21411-53-0
MSDS
Details
Source
Streptomyces virginiae
Fermentek product Code
VIM-001
Brand/grade
For research
Specifications
Appearance
White to slight yellow powder
Purity by HPLC
≥97% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
165°C-170°C (decompose)
Solubility test
Clear colorless to light yellow solution at 5 mg/ml of Dichloromethane
Chemical identification
Names and identifiers
Synonyms: Streptogramin A; Mikamycin A; Staphilomycin; Ostreogrycin A; Virginiamycin M1 Pristinamycin IIA;
EU number
244-376-6
Description
Virginiamycin M1 is a macrolide antibiotic which interacts with the bacterial 50S ribosome, inhibiting its function in a reversible manner.
Activity of Virginiamycin M1 at the ribosome blocks translation and produces a bacteriostatic effect.
With addition of Virginiamycin S1 the two antibiotics produce a synergistic bacteriocidal effect.
InChl Key
DAIKHDNSXMZDCU-FQTGFAPKSA-N
Canonical SMILES
CC1C=CC(=O)NCC=CC(=CC(CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)OC1C(C)C)O)C
Isomeric SMILES
C[C@@H]1/C=C/C(=O)NC/C=C/C(=C/[C@H](CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)O[C@@H]1C(C)C)O)/C
Further Information
Solubility ( literature )
Virginiamycin M1 is soluble in ethanol (3-4%) , methanol (3-4%), DMSO, Dichloromethane, DMF, and sparingly, in water.
Compound Classification
Cyclic peptide antibiotic, of Streptogramin group
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Fermentek Product Category
Signal to sort
V
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