Triacsin C

Molecular Formula

C11H17N3O

M.W.

207.27

CAS number

76896-80-5

MSDS

Download

Details

Source

Streptomyces aureofaciens

Fermentek product Code

TRC-001

Brand/grade

For research

Specifications

Appearance

Off-white to Dark yellow powder

Purity by HPLC

≥90% ; refer to CoA for more data

Purity By TLC

≥95% ; refer to CoA for more data

Solubility test

Clear yellowish to yellow solution at 5mg/ml of Methanol or DMSO

Chemical identification

Names and identifiers

Synonyms

2E, 4E, 7E-Undecatriene-1-triazene
1-hydroxy-3-(2',4',7'-undecatrienylidine)triazene

EU number

616-408-2

Chemical name

2,4,7-Undecatrienal, nitrosohydrazone, (2E,4E,7E)-

Description

Triacsin C, an analog of polyunsaturated fatty acid. A potent vasodilator.

InChl Key

NKTGCVUIESDXPU-YLEPRARLSA-N

Canonical SMILES

CCCC=CCC=CC=CC=NNN=O

Isomeric SMILES

CCC/C=C/C/C=C/C=C/C=N/NN=O

Further Information

Solubility ( literature )

Soluble to 25 mM in DMSO (lit)

Compound Classification

Chemical classification:

Triazene class compound
Polyunsaturated fatty acid analog.

Classification by bioactivities:

Arachidonoyl-CoA synthetase inhibitor
Inhibits Synthesis of triacylglycerol and phospholipid
Apoptosis inhibitor
Vasodilator

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Protect from moisture

Protect from light !

Avoid exposing to strong direct light.

Store under argon.

Other vendors may recommend higher temperatures for storage.

Attention: this compound may deteriorate quickly if stored improperly

Retest time

1.5 Years

Applications

Selectively inhibits arachidonoyl-CoA synthetase in intact cells. Inhibits the nonspecific acyl-CoA synthetase in cell sonicates. Inhibits neutrophil functions. Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice.

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Composition

Ingredient type

Fermentek product

Special Info

Available since

2007