Triacsin C
Molecular Formula
C11H17N3O
M.W.
207.27
CAS number
76896-80-5
MSDS
Source
Streptomyces aureofaciens
Fermentek product Code
TRC-001
Brand/grade
For research
Appearance
Off-white to Dark yellow powder
Purity by HPLC
≥90% ; refer to CoA for more data
Purity By TLC
≥95% ; refer to CoA for more data
Solubility test
Clear yellowish to yellow solution at 5mg/ml of Methanol or DMSO
Names and identifiers

Synonyms

  • 2E, 4E, 7E-Undecatriene-1-triazene
  • 1-hydroxy-3-(2',4',7'-undecatrienylidine)triazene

 

EU number
616-408-2
Chemical name
2,4,7-Undecatrienal, nitrosohydrazone, (2E,4E,7E)-
Description

Triacsin C, an analog of polyunsaturated fatty acid. A potent vasodilator.

InChl Key
NKTGCVUIESDXPU-YLEPRARLSA-N
Canonical SMILES
CCCC=CCC=CC=CC=NNN=O
Isomeric SMILES
CCC/C=C/C/C=C/C=C/C=N/NN=O
Solubility ( literature )

Soluble to 25 mM in DMSO (lit)

Compound Classification

Chemical classification:

  • Triazene class compound
  • Polyunsaturated fatty acid analog.

Classification by bioactivities:

  • Arachidonoyl-CoA synthetase inhibitor
  • Inhibits Synthesis of triacylglycerol and phospholipid
  • Apoptosis inhibitor
  • Vasodilator
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Protect from light !
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Attention: this compound may deteriorate quickly if stored improperly
Retest time
1.5 Years
Applications

Selectively inhibits arachidonoyl-CoA synthetase in intact cells. Inhibits the nonspecific acyl-CoA synthetase in cell sonicates. Inhibits neutrophil functions. Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Inhibitor of:
Value
Selective inhibitor of acyl-CoA synthetase
Title
Transport information
Value
Not hazardous for transport
Title
Specifications updated 24-October 2017
Value
Purity ≥90% by HPLC
Signal to sort
T