Streptozotocin

Molecular Formula

C8H15N3O7

M.W.

265.22

CAS number

18883-66-4

Details

Source

Streptomyces sp.

Fermentek product Code

STZ-001

Brand/grade

For research

Specifications

Appearance

White to pale yellow powder

Purity by HPLC

≥98% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

120°C-125°C

Solubility test

Clear colorless solution at 50mg/ml Water, Clear colorless solution at 10mg/ml Ethanol

Chemical identification

Names and identifiers

Streptozocin, Streptozotocin, ZanosarD-Glucopyranose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-Glucose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)-

RTECS: LZ5775000

EU number

242-646-8

Description

Streptozotocin is a natural glucosamine nitrosourea antibiotic.

InChl Key

ZSJLQEPLLKMAKR-UHFFFAOYSA-N

Canonical SMILES

CN(C(=O)NC1C(C(C(OC1O)CO)O)O)N=O

Further Information

Solubility ( literature )

Water soluble 5g/L at 25°C

Compound Classification

glucosamine nitrosourea antibiotic

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Protect from moisture

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Other vendors may recommend higher temperatures for storage.

Retest time

3 Years

Applications

Streptozocin is used to induce Type 1 diabetes for medical research.Streptozotocin is used in medicine since 1982 as a drug against certain cancers of the Langerhans Islets. It is cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Composition

Ingredient type

Fermentek product

Special Info

Available since

2012