Sinefungin
Molecular Formula
C15H23N7O5
M.W.
381.39
CAS number
58944-73-3
MSDS
Details
Source
Streptomyces sp.
Fermentek product Code
SN
Brand/grade
For research
Specifications
Appearance
White to yellow powder
Purity by HPLC
≥96% ; refer to CoA for more data
Purity By TLC
≥96% ; refer to CoA for more data
Solubility test
Clear colorless solution at 20mg/ml of water
Chemical identification
Names and identifiers
Synonym:
RTECS: HE3140000
UPAC Name: (2S,5S)-2,5-diamino-6-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]hexanoic acid
EU number
637-385-5
Description
Natural antibiotic containing adenine, sugar hydroxyl and amino groups; exhibiting Antifungal ,Antimalarial and Antiprotozoal properties.
InChl Key
LMXOHSDXUQEUSF-YECHIGJVSA-N
Canonical SMILES
C1=NC2=C(C(=N1)N)N=CN2C3C(C(C(O3)CC(CCC(C(=O)O)N)N)O)O
Isomeric SMILES
C1=NC2=C(C(=N1)N)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)N)O)O
Further Information
Solubility ( literature )
Good water solubility. Soluble in ethanol, methanol, DMF or DMSO (lit.)
Compound Classification
Chemical class:
- Adenosine analog
- Nucleoside antibiotic
Biological activity:
- Antifungal
- Antimalarial
- Antiprotozoal
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Applications
Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2 Antifungal Antimalarials Antiprotozoal
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Title
Transport information
Value
Not hazardous for transport
Title
toxicity by RTECS oral mouse LD50
Value
1 gram/kg
Fermentek Product Category
Signal to sort
S
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