Ionomycin free acid
Molecular Formula
C41H72O9
M.W.
709.01
CAS number
56092-81-0
MSDS
Source
Streptomyces conglobatus
Fermentek product Code
IOF-001
Appearance
Waxy material
Purity by HPLC
≥97% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Methanol; Clear colorless solution at 10mg/ml of DMSO; Clear colorless solution at 10mg/ml of DCM
Names and identifiers

(4R,6S,8S,10Z,12R,14R,16E,18S,19S,20R,21S)-11,19,21-Trihydroxy-22-{(2S,2'S,5S,5'R)-5'-[(1S)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9-oxo-10,16-docosadi enoic acid

RTECS : NO0600000

EU number
611-356-7
Description

Ionomycin : a Ca++ ionophore

InChl Key
PGHMRUGBZOYCAA-ADZNBVRBSA-N
Canonical SMILES
CC(CCC(=O)O)CC(C)CC(C)C(=O)C=C(C(C)CC(C)CC=CC(C)C(C(C)C(CC1CCC(O1)(C)C2CCC(O2)(C)C(C)O)O)O)O
Isomeric SMILES
C[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)\O
Solubility ( literature )

DMSO, Ethanol, Methanol

Compound Classification
  • Unsaturated fatty acid antibiotic.
  • Calcium Ionophore
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Ionomycin is more effective than A23187 as a Ca++ionophore. Ionomycin is used in research on Ca++ transport across biological membranes; Ionomycin induces apoptotic degeneration of embryonic cortical neuron

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport safety information
Value
Nor hazardous goods
Fermentek Product Category
Signal to sort
I