Alamethicin

Molecular Formula

C92H150N22O25

M.W.

1 964.30

CAS number

27061-78-5

MSDS

Download

Details

Source

Trichoderma viride

Fermentek product Code

ALA-001

Brand/grade

For research

Specifications

Appearance

Off White to Beige powder

Purity by HPLC

4 peaks, complies to standard

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

252°C-272°C

Solubility test

Clear colorless solution at 10mg/ml DMSO or Methanol

Chemical identification

Names and identifiers

Synonyms: Antibiotic U 22324

RTECS: AY1900000

EU number

608-040-6

Description

Alamethicin is a channel-forming ionophore. Chemically, it is a peptide of 20 amino acids. The product consists of a mixture of several isoforms, which may be slightly different in the amino-acids sequences, but possess the same activity.

InChl Key

LGHSQOCGTJHDIL-UTXLBGCNSA-N

Canonical SMILES

CC(C)CC(C(=O)NC(C)(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CC=CC=C2)CO)NC(=O)CNC(=O)C(C)(C)NC(=O)C(C(C)C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C3CCCN3C(=O)C(C)(C)NC(=O)C

Isomeric SMILES

C[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)NC(C)(C)C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC2=CC=CC=C2)CO)NC(=O)C(C)(C)NC(=O)[C@H](C)NC(=O)C(C)(C)NC(=O)[C@@H]3CCCN3C(=O)C(C)(C)NC(=O)C

Further Information

Solubility ( literature )

DMSO, Methanol, Ethanol

Compound Classification