PX-866 (Sonolisib)
Molecular Formula
C29H35NO8
M.W.
525.59
CAS number
502632-66-8
MSDS
Details
Source
Semisynthetic
Fermentek product Code
PX8-001
Brand/grade
For research
Specifications
Appearance
Orange powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
120°C-130°C
Solubility test
Clear yellowish solution at 10mg/ml of Methanol or DMSO
Chemical identification
Names and identifiers
Synonym:
Sonolisib
Chemical name:
- (1E,4S,4aR,5R,6aS,9aR)-5-(acetyloxy)-1-[(di-2-propen-1-ylamino)methylene]-4,4a,5,6,6a,8,9,9a-octahydro-11-hydroxy-4-(methoxymethyl)-4a,6a-dimethyl-cyclopenta[5,6]naphtho[1,2-c]pyran-2,7,10(1H)-trione
- Sonolisib
EU number
812-171-6
Description
PX-866 is a synthetic derivate of wortmannin.
InChl Key
QIUASFSNWYMDFS-NILGECQDSA-N
Canonical SMILES
CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C(=CN(CC=C)CC=C)C4=C(C3=O)O)COC)C)C
Isomeric SMILES
CC(=O)O[C@@H]1C[C@]2([C@@H](CCC2=O)C3=C1[C@]4([C@H](OC(=O)/C(=C/N(CC=C)CC=C)/C4=C(C3=O)O)COC)C)C
Further Information
Solubility ( literature )
Methanol , DMSO, Ethyl acetate, Ethanol
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications
- Potential anti-cancer agent;
- Phosphatidylinositol 3-kinase inhibitor
Disclaimer
For Research use only
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Fermentek Product Category
Signal to sort
P
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