Filipin III

Molecular Formula

C35H58O11

M.W.

654.83

CAS number

480-49-9

Details

Source

Streptomyces filipinensis

Fermentek product Code

FLP-002

Brand/grade

For research

Specifications

Appearance

White to slight yellow

Purity by HPLC

≥95% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Solubility test

Clear colorless solution at 10mg/ml of Methanol

Chemical identification

Names and identifiers

Synonyms:

Desoxylagosin
Filimarisin
Filipin

Chemical names:

IUPAC: (17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one

RTECS# RN9800000

EU number

637-175-3

Description

Filipin III, a polyene (pentaene) macrocyclic lactone broad spectrum antifungal antibiotic, also exhibits antitumor and antiviral activities. It acts by binding cell membrane sterols, disrupting membrane integrity. Filipin III, the most abundant component of Filipin complex is offered in pure form.

InChl Key

IMQSIXYSKPIGPD-YQRUMEKGSA-N

Canonical SMILES

CCCCCC(C1C(CC(CC(CC(CC(CC(CC(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O

Isomeric SMILES

CCCCCC(C1C(CC(CC(CC(CC(CC(CC(/C(=C/C=C/C=C/C=C/C=C/C(C(OC1=O)C)O)/C)O)O)O)O)O)O)O)O

Further Information

Compound Classification

Warning! This substance causes serious eye irritation, causes skin irritation and may cause respiratory irritation.

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C

Open carefully.