HT2 toxin

HT2 toxin
Molecular Formula
C22H32O8
M.W.
424.48
CAS number
26934-87-2
MSDS
Source
Semisynthetic
Fermentek product Code
HT2-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 5mg/ml Dichloromethane
Names and identifiers

Systemic name: Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate

RTECS: YD0050000

EU number
621-720-7
Description

HT2 Toxin is a trichothecene group mycotoxin; naturally found in spoiled foods.

InChl Key
PNKLMTPXERFKEN-CKRUGLOOSA-N
Canonical SMILES
CC1=CC2C(CC1OC(=O)CC(C)C)(C3(C(C(C(C34CO4)O2)O)O)C)COC(=O)C
Isomeric SMILES
CC1=C[C@@H]2[C@](C[C@@H]1OC(=O)CC(C)C)(C3([C@@H]([C@H]([C@H](C34CO4)O2)O)O)C)COC(=O)C
Solubility ( literature )

Dichloromethane, DMSO, Ethanol, Ethyl Acetate. Slightly soluble in petroleum ether; very slightly soluble in water.

Compound Classification

Trichothecene mycotoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Transport safety: class 6.1 PG I
Available since
Title
Transport information
Value
PG I
Title
Deleted CAS Numbers
Value
61356-56-7; 116163-63-4; 145427-92-5
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Regulated Mycotoxins
Trichocothecenes
Signal to sort
H

Quote for

Price
$1.00
HT-2_toxin.gif
HT-2_toxin.gif

Diacetoxyscirpenol (DAS)

Diacetoxyscirpenol (DAS)
Molecular Formula
C19H26O7
M.W.
366.41
CAS number
2270-40-8
Source
Fusarium sp
Fermentek product Code
DAS-001
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
160°C-165°C
Solubility test
Clear colorless solution at 10mg/ml Methanol ; Clear colorless solution at 10mg/ml dichloromethane
Names and identifiers

Synonyms

  • Anguidine,
  • DAS
  • Diacetoxyscirpenol

RTECS YD0112000

 

EU number
218-873-3
Description

Diacetoxyscirpenol (DAS) also known as Anguidine,  is a mycotoxin belonging to 12,13-epoxytrichothecene group, produced by several Fusarium strains together with some other toxins such as T2 and HT2 toxins.

 DAS inhibits initiation of protein synthesis, causing the death of intensively replicating cells. By the virtue of this effect, DAS possesses teratogenic and anti proliferatory properties. Consequently,  DAS attracts interest as a potential cancer- drug.

 

 

InChl Key
AUGQEEXBDZWUJY-ZLJUKNTDSA-N
Canonical SMILES
CC1=CC2C(CC1)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C
Isomeric SMILES
CC1=C[C@@H]2[C@](CC1)([C@]3([C@@H]([C@H]([C@H]([C@]34CO4)O2)O)OC(=O)C)C)COC(=O)C
Solubility ( literature )

Soluble in moderately polar solvents, such as chloroform, diethyl ether, ethyl acetate, and acetone

Compound Classification
  • trichothecene mycotoxin
  • Apoptosis inducer
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Diacetoxyscirpenol (Anguidine) and its derivates possess anticancer properties. Diacetoxyscirpenol (Anguidine) inhibits initiation of protein synthesis, resulting in the death of rapidly proliferating cells. Diacetoxyscirpenol (Anguidine) also has been shown to both potentiate and protect against the cytotoxic effects of other drugs. There were 14 clinical trials reported, all in the area of colorectal tumors and leukemia. No records found after 1985. Apoptosis inducement.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Deleted CAS Numbers
Value
11011-10-2 ; 22135-66-6 ; 25662-95-7 ; 28776-47-8 ; 109547-11-7 ; 145427-91-4 ; 852223-87-1 ;
Title
Transport information
Value
Pg II
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Regulated Mycotoxins
Trichocothecenes
Research field: Cancer
Apoptosis related
Protein synthesis inhibitors
Signal to sort
D

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Price
$1.00
Diacetoxyscirpenol.gif
Diacetoxyscirpenol.gif

Standard Solution Aflatoxin Mixture

Standard Solution Aflatoxin Mixture
MSDS
Fermentek product Code
STD-010
Brand/grade
Analytical standard
Description

Mixture of four Aflatoxin species: Aflatoxin B1, 0.5 ppm; Aflatoxin B2 , 0.5 ppm Aflatoxin G1, 0.5 ppm Aflatoxin G2, 0.5 ppm in Acetonitrile "HPLC-Supra-Gradient" grade. Ready for Injection into HPLC system; Please refer to the certificate of analysis for the exact concentrations of the toxins in the solution. Available in 1 ml or 5 ml vials.

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Disclaimer
Refer to MSDS for further safety and handling instructions.
Ingredient Reference
Aflatoxin B1
Ingredient type
Fermentek product
Ingredient amount
0.5μg/ml in Acetonitrile
Ingredient Reference
Aflatoxin B2
Ingredient type
Fermentek product
Ingredient amount
0.5μg/ml in Acetonitrile
Ingredient Reference
Aflatoxin G1
Ingredient type
Fermentek product
Ingredient amount
0.5μg/ml in Acetonitrile
Ingredient Reference
Aflatoxin G2
Ingredient type
Fermentek product
Ingredient amount
0.5μg/ml in Acetonitrile
Ingredient Other
Acetonitril, HPLC grade
Ingredient type
Fermentek product
Ingredient amount
to 100%
Amber-glass vials, 1 or 5 ml
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Aflatoxins
Regulated Mycotoxins
Standard Solutions
Signal to sort
S

Quote for

Price
$1.00

Aflatoxin M2

Aflatoxin M2
Molecular Formula
C17H14O7
M.W.
330.29
CAS number
6885-57-0
MSDS
Source
Semisynthetic
Fermentek product Code
AFM-002
Brand/grade
For research
Appearance
Off white to yellowish powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 1mg/ml Dichloromethane
Names and identifiers

4-hydroxyaflatoxin B2

IUPAC:     (6aR,9aR)-9a-Hydroxy-4-methoxy-2,3,6a,8,9,9a-hexahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione

RTECS: GY1720000

 

EU number
229-989-9
Chemical name
4-hydroxyaflatoxin B2
Description

A potent hepatotoxic and hepatocarcinogenic mycotoxin, found in milk of cows fed on meal contaminated with aflatoxin B2

InChl Key
OQLKWHFMUPJCJY-UHFFFAOYSA-N
Canonical SMILES
COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)OC5C4(CCO5)O
Solubility ( literature )

DMSO or MeOH

Compound Classification
  • Furano-furano-Benzopyran mycotoxin
  • Aflatoxin class toxin.
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

Potent liver carcinogen and DNA-damaging agent.

It is also mutagenic, teratogenic, and causes immunosuppression in animals.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Semi-Synthetic
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
PG I
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Aflatoxins
Regulated Mycotoxins
Signal to sort
A

Quote for

Price
$1.00

Aflatoxin M1

Aflatoxin M1
Molecular Formula
C17H12O7
M.W.
328.27
CAS number
6795-23-9
MSDS
Source
Aspergillus flavus
Fermentek product Code
AFM-001
Brand/grade
For research
Appearance
White to slight yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 1mg/ml Methanol:ACN (1:1)
Names and identifiers

Chemical names: 4-hydroxyaflatoxin B1

RTECS:  GY1880000

 

EU number
229-865-4
Description

Aflatoxin M1 is a potent hepatotoxic and hepatocarcinogenic mycotoxin, found in milk of cows fed on meal contaminated with Aflatoxin B1

InChl Key
MJBWDEQAUQTVKK-IAGOWNOFSA-N
Canonical SMILES
COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)OC5C4(C=CO5)O
Isomeric SMILES
COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C(=C1)O[C@@H]5[C@]4(C=CO5)O
Solubility ( literature )

Methanol, DMSO

Compound Classification

Furano-furano-Benzopyranmycotoxin

Aflatoxin

Storage, handling
4°C. Protect from light
Retest time
3 Years
Applications

Potent liver carcinogen and DNA-damaging agent.It is also mutagenic, teratogenic, and causes immunosuppression in animals.

Ingredient type
Fermentek product
Available since
Title
Transport information
Value
PG I
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Aflatoxins
Regulated Mycotoxins
Cytotoxic agents
Signal to sort
A

Quote for

Price
$1.00
Aflatoxin_M1
Aflatoxin_M1

Aflatoxin G2

Aflatoxin G2
Molecular Formula
C17H14O7
M.W.
330.29
CAS number
7241-98-7
MSDS
Source
Aspergillus flavus
Fermentek product Code
AFG-002
Brand/grade
For research
Appearance
Off - white powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 5mg/ml Dichloromethane
Names and identifiers
  • Dihydroaflatoxin G1
  • HSDB 3456
  • IUPAC(7aR,cis)-3,4,7a,9,10,10a-hexahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione
  • RTECS:  LV1700000
EU number
230-643-4
Description

9,10-dihidro derivate of aflatoxin G1. A potent hepatotoxic and hepatocarcinogenic mycotoxin

InChl Key
WPCVRWVBBXIRMA-WNWIJWBNSA-N
Canonical SMILES
COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4C5CCOC5OC4=C1
Isomeric SMILES
COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4[C@@H]5CCO[C@@H]5OC4=C1
Solubility ( literature )

DMSO or Methanol

Compound Classification
  • Furano-furano-Benzopyranmycotoxin
  • Aflatoxin
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Retest time
3 Years
Applications

Potent liver carcinogen and DNA-damaging agent.It is also mutagenic, teratogenic, and causes immunosuppression in animals.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Customs: Laboratory reagents-38220000
Transport safety: class 6.1 PG II
Available since
Title
Transport information
Value
PG I
Title
CN code
Value
29322090
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Regulated Mycotoxins
Signal to sort
A

Quote for

Price
$1.00
Aflatoxin_G2
Aflatoxin_G2

Aflatoxin G1

Aflatoxin G1
Molecular Formula
C17H12O7
M.W.
328.27
CAS number
1165-39-5
MSDS
Source
Aspergillus flavus
Fermentek product Code
AFG-001
Brand/grade
For research
Appearance
White to slight yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless to yellow solution at 5mg/ml Dichloromethane
Names and identifiers

UPAC : (7aR,cis)-3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione

HSDB 3455

RTECS :    

 

EU number
214-615-9
Description

Aflatoxin G1, potent hepatotoxic and hepatocarcinogenic mycotoxin

InChl Key
XWIYFDMXXLINPU-UHFFFAOYSA-N
Canonical SMILES
COC1=C2C3=C(C(=O)OCC3)C(=O)OC2=C4C5C=COC5OC4=C1
Solubility ( literature )

DMSO or Methanol

Compound Classification

Furano-furano-BenzopyranmycotoxinAflatoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Retest time
3 Years
Applications

Potent liver carcinogen and DNA-damaging agent.It is also mutagenic, teratogenic, and causes immunosuppression in animals.

Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
PG I
Title
CN code
Value
2932 20 90
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Aflatoxins
Regulated Mycotoxins
Signal to sort
A

Quote for

Price
$1.00
Aflatoxin_G1
Aflatoxin_G1

Aflatoxin B2

Aflatoxin B2
Molecular Formula
C17H14O6
M.W.
314.29
CAS number
7220-81-7
MSDS
Source
Aspergillus flavus
Fermentek product Code
AFB-002
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
290°C-316°C
Solubility test
Clear colorless solution at 5mg/ml Dichloromethane
Names and identifiers

Dihydroaflatoxin B

HSDB 3454

RTECS: GY1720000

 

 

EU number
230-618-8
Description

8,9-dihidro derivate of aflatoxin B1.

A potent hepatotoxic and hepatocarcinogenic mycotoxin

InChl Key
WWSYXEZEXMQWHT-WNWIJWBNSA-N
Canonical SMILES
COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5CCOC5OC4=C1
Isomeric SMILES
COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4[C@@H]5CCO[C@@H]5OC4=C1
Solubility ( literature )

DMSO or MeOH

Compound Classification

Furano-furano-Benzopyran-mycotoxin

Aflatoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Available since
Title
Transport information
Value
PG I
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Aflatoxins
Regulated Mycotoxins
Cytotoxic agents
Signal to sort
A

Quote for

Price
$1.00
Aflatoxin_B2
Aflatoxin_B2

Aflatoxin B1

Aflatoxin B1
Molecular Formula
C17H12O6
M.W.
312.27
CAS number
1162-65-8
MSDS
Source
Aspergillus flavus
Fermentek product Code
AFB-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
260°C-269°C
Solubility test
Clear colorless solution at 10 mg/ml of Dichloromethane
Names and identifiers

2,3,6aα,9aα-tetrahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione

HSDB 3453

EU number
214-603-3
Description

Aflatoxin B1 is a potent hepatotoxic and hepatocarcinogenic mycotoxin. It is also mutagenic, teratogenic, and causes immunosuppression in animals.

InChl Key
OQIQSTLJSLGHID-WNWIJWBNSA-N
Canonical SMILES
COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4C5C=COC5OC4=C1
Isomeric SMILES
COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C4[C@@H]5C=CO[C@@H]5OC4=C1
Solubility ( literature )

May be dissolved in DCM, DMSO or Methanol

Compound Classification

Furano-furano-Benzopyran mycotoxin Aflatoxin

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Open carefully – Lyophilized solid under vacuum
Retest time
3 Years
Ingredient type
Fermentek product
Shipped in amber-glass vials
Transport safety: class 6.1 PG I
Available since
Title
Transport information
Value
PG I
Title
HS FER recommendation
Value
Laboratory reagents or reference material-38220000
Title
HS--EU
Value
Heterocyclic compounds wi/ oxygen hetero-atom(s) only; lactones; other
Fermentek Product Category
Food Safety
Mycotoxins
Food Safety Related
Aflatoxins
Regulated Mycotoxins
Cytotoxic agents
Signal to sort
A

Quote for

Price
$1.00
Aflatoxin_B1
Aflatoxin_B1
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