Forskolin
Molecular Formula
C22H34O7
M.W.
410.50
CAS number
66575-29-9
MSDS
Details
Source
Coleus forskohlii (plant extract)
Fermentek product Code
FOR-001
Brand/grade
For research
Specifications
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
220°C-230°C
Solubility test
Clear colorless solution at 10mg/ml EtOAc
Chemical identification
Names and identifiers
EU number
266-410-9
Description
Forskolin is a labdane diterpene that is produced by Coleus forskohlii
InChl Key
OHCQJHSOBUTRHG-KGGHGJDLSA-N
Canonical SMILES
CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O
Isomeric SMILES
CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O
Further Information
Solubility ( literature )
Forskolin is soluble in DMSO, Methanol, Ethanol, Dichloromethane, Forskolin may be dissolved in 2% ethanol in water, by dissolving it first in Ethanol and subsequently diluting this solution with water.
Compound Classification
- diterpene antibiotic
- vasodilator
Storage, handling
Room temperature or below. Light protection is recommended by other sources.
Retest time
3 Years
Applications
- Bronchodilator agent, Agents that cause an increase in the expansion of a bronchus or bronchial tubes.
- Cardiotonic agent: Agents that have a strengthening effect on the heart or that can increase cardiac output.
- Vasodilator agent: Agent causing dilation of the blood vessels.
- Forskolin activates Adenylate Cyclase, thus increasing the cyclic AMP intra-cellular concentration. Forskolin is commonly used to raise levels of cyclic AMP (cAMP) in the study and research of cell physiology. Forskolin has been mentioned as a possible weight loss aid, and as a mean to treat Glaucoma, as it may reduce the intraocular pressure. See also United States Patent Application 20100168014
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Fermentek Product Category
Signal to sort
F
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