Verrucarin A
Molecular Formula
C27H34O9
M.W.
502.55
CAS number
3148-09-2
MSDS
Source
Myrothecium sp.
Fermentek product Code
VRA-001
Brand/grade
For research
Appearance
White to faint yellow powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless to faint yellow solution at 10mg/ml of DMSO or Chloroform
Names and identifiers

Synonyms:

  • Muconomycin A
  • Spiro[16,18-methano-1H,3H,23H-[1,6,12]trioxacyclooctadecino[3,4-d][1]benzopyran-17(18H),2'-oxirane]-3,9,14-trione, 4,5,6,7,16,16a,19a,22-octahydro-4-hydroxy-5,16a,21-trimethyl-, (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-
  • Verrucarine A

Chemical names:

IUPAC: 

  •  (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4,5,6,7,16,16a,19a,22-Octahydro-4-hydroxy-5,16a,21-trimethylspiro[16,18-methano-1H,3H,23H-[1,6,12]trioxacyclooctadecino[3,4-d][1]benzopyran-17(18H),2'-oxirane]-3,9,14-trione

Merck index:  M11430  (Verrucarins)

EU number
636-535-7
Description

Verrucarin A is a type D trichothecene  from Stachybotrys, Fusarium, and Myrothecium fungi,  which inhibits protein synthesis and causes apoptosis.

InChl Key
NLUGUZJQJYVUHS-IDXDZYHTSA-N
Canonical SMILES
CC1CCOC(=O)C=CC=CC(=O)OC2CC3C4(C2(C5(CCC(=CC5O3)C)COC(=O)C1O)C)CO4
Isomeric SMILES
C[C@@H]1CCOC(=O)/C=C/C=C\C(=O)O[C@@H]2C[C@@H]3[C@]4([C@]2([C@]5(CCC(=C[C@H]5O3)C)COC(=O)[C@H]1O)C)CO4
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Ingredient type
Fermentek product
Transport safety: class 6.1 PG ||
Available since
Title
Depreciated CAS Registry Numbers
Value
11039-36-4 18046-08-7 21462-53-3
Fermentek Product Category