Penitrem B

Penitrem B
Molecular Formula
C37H45NO5
M.W.
583.76
CAS number
11076-67-8
Source
Penicillium palitans
Fermentek product Code
PEB
Brand/grade
For research
Appearance
White to off white powder
Purity by HPLC
≥ 95% ; refer to CoA for more data
Solubility test
Clear colorless solution at 50mg/ml of DMSO
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms: 

  • Tremortin B
  • Penitrem B

Chemical names:

IUPAC:  (1S,2R,5S,6S,8R,9S,10R,12S,15R,16S,25S,27S,28S)-15,16,33,33-tetramethyl-24-methylidene-10-prop-1-en-2-yl-7,11,32-trioxa-18-azadecacyclo[25.4.2.02,16.05,15.06,8.06,12.017,31.019,30.022,29.025,28]tritriaconta-17(31),19(30),20,22(29)-tetraene-5,9-diol

RTECS# RY753700

EU number
Not listed as at 16-June-2024
Chemical name
Penitrem B
Description

Penitrem B is a tremogenic toxin produced by some Penicillium species, such as P. palitans, P.aurantiogriseum P.verrucosum, and other genera (Aspergillus sulphureus).  As a tremorgenic mycotoxin, it may affect central nervous system activity.

InChl Key
CRPJNVUYZRFGAK-WKAGVDCZSA-N
Canonical SMILES
CC(=C)C1C(C2C3(O2)C(O1)CCC4(C3(CCC5C4(C6=C7C5OC(C8CC9C8C1=C(CC9=C)C=CC(=C17)N6)(C)C)C)O)C)O
Isomeric SMILES
CC(=C)[C@@H]1[C@@H]([C@@H]2[C@@]3(O2)[C@@H](O1)CC[C@]4([C@]3(CC[C@@H]5[C@@]4(C6=C7[C@H]5OC([C@H]8C[C@H]9[C@@H]8C1=C(CC9=C)C=CC(=C17)N6)(C)C)C)O)C)O
Solubility ( literature )

Methanol, DMSO

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C.
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Protect from moisture!
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings
Ingredient type
Fermentek product
Customs: Other Antibiotics-29419000
Shipped at ambient temperature
Shipped in amber-glass vials
Available since
Fermentek Product Category
Signal to sort
P