Skull and crossbones

Penitrem B

Molecular Formula

C37H45NO5

M.W.

583.76

CAS number

11076-67-8

Details

Source

Penicillium palitans

Fermentek product Code

PEB

Brand/grade

For research

Specifications

Appearance

White to off white powder

Purity by HPLC

≥ 95% ; refer to CoA for more data

Solubility test

Clear colorless solution at 50mg/ml of DMSO
Clear colorless solution at 10mg/ml of Methanol

Chemical identification

Names and identifiers

Synonyms:

Tremortin B
Penitrem B

Chemical names:

IUPAC: (1S,2R,5S,6S,8R,9S,10R,12S,15R,16S,25S,27S,28S)-15,16,33,33-tetramethyl-24-methylidene-10-prop-1-en-2-yl-7,11,32-trioxa-18-azadecacyclo[25.4.2.0^2,16.0^5,15.0^6,8.0^6,12.0^17,31.0^19,30.0^22,29.0^25,28]tritriaconta-17(31),19(30),20,22(29)-tetraene-5,9-diol

RTECS# RY753700

EU number

Not listed as at 16-June-2024

Chemical name

Penitrem B

Description

Penitrem B is a tremogenic toxin produced by some Penicillium species, such as P. palitans, P.aurantiogriseum P.verrucosum, and other genera (Aspergillus sulphureus). As a tremorgenic mycotoxin, it may affect central nervous system activity.

InChl Key

CRPJNVUYZRFGAK-WKAGVDCZSA-N

Canonical SMILES

CC(=C)C1C(C2C3(O2)C(O1)CCC4(C3(CCC5C4(C6=C7C5OC(C8CC9C8C1=C(CC9=C)C=CC(=C17)N6)(C)C)C)O)C)O

Isomeric SMILES

CC(=C)[C@@H]1[C@@H]([C@@H]2[C@@]3(O2)[C@@H](O1)CC[C@]4([C@]3(CC[C@@H]5[C@@]4(C6=C7[C@H]5OC([C@H]8C[C@H]9[C@@H]8C1=C(CC9=C)C=CC(=C17)N6)(C)C)C)O)C)O

Further Information

Solubility ( literature )

Methanol, DMSO

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C.

Open carefully.

Use the original container to store the product.

Keep the lid tightly closed.

Avoid exposing to strong direct light.

Other vendors may recommend higher temperatures for storage.

Protect from moisture!

Disclaimer

For Research use only

Not for Human or Drug use

Not extracted from humans or animals

Refer to MSDS for further safety and handling instructions

Warnings