Cancer is most accurately described as a class of diseases characterized by uncontrolled cell growth and division.There are more than a hundred defined types of cancer.

Cancer can occur in nearly every organ or tissue in the body.

Various small molecules are widely used in the research of cancer. Especially in the last decade, cancer research has evolved from a one-size-fits-all approach that emphasized cytotoxic chemotherapy to a more personalized medical strategy that focuses on the discovery and development of targeted drugs.

These drugs are designed, on a molecular level, to exploit particular genetic dependencies, addictions, and vulnerabilities of cancer cells.

Much current cancer research is concentrated in the areas of programmed cell death, tumor invasion and angiogenesis, tumor immunology, oncogenic signaling, gene expression and copy number, epigenetic regulation, toxicity and chemoresistance, metabolic stress and damage to DNA. Fermentek offers more than 30 unique biochemicals currently being used in cancer research.

15-Acetoxyscirpenol

15-Acetoxyscirpenol
Molecular Formula
C17H24O6
M.W.
324.37
CAS number
2623-22-5
MSDS
Source
Semisynthetic
Fermentek product Code
15A-001
Brand/grade
For research
Appearance
White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
160-167°C
Solubility test
Clear colorless solution at 10 mg/ml Methanol;
Clear colorless solution at 10 mg/ml DMSO
Names and identifiers

Synonyms

MAS

15-Acetoxyscirpenol

15-Monoacetoxyscirpenol

15- Deacetylanguidin

4- Deacetylanguidin

IUPAC names:  15-Acetoxyscirpenol

Chemical names: 15-Mono-O-acetylscirpenol;    Deacetylanguidin;    15-Acetoxyscirpenol;

Systematic Name:  Trichothec-9-ene-3-alpha,4-beta,15-triol, 12,13-epoxy-, 15- acetate

RTECS: YD0111000

EU number
636-756-9
Chemical name
15-Acetoxyscirpenol;
Description

MAS (15-Acetoxyscirpenol) is a Trichothecene class mycotoxin. It is closely related to DAS (Diacetoxyscirpenol)

InChl Key
IRXDUBNENLKYTC-DIRMQTSCSA-N
Canonical SMILES
CC1=CC2C(CC1)(C3(C(C(C(C34CO4)O2)O)O)C)COC(=O)C
Isomeric SMILES
CC1=C[C@@H]2[C@](CC1)(C3([C@@H]([C@H]([C@H](C34CO4)O2)O)O)C)COC(=O)C
Solubility ( literature )

Soluble in moderately polar solvents, such as chloroform, diethyl ether, ethyl acetate, and acetone

Compound Classification

Trichothecene

Mycotoxin

Apoptosis inducer

UNSPSC:

123521 Chemicals, including biochemicals.

121615 Chemicals, Additives, Indicators and reagents    

85151701 Healthcare Services;  Food and nutrition services; Food policy planning and aid; Food standards

85131703  Biomedical research services

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Use the original container to store the product.
Keep the lid tightly closed.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Applications

MAS, as many other anguidine derivates exhibits a strong antimitotic effect,

Disclaimer
Semi-Synthetic
Degree
Grain
Ingredient type
Fermentek product
Title
Transport information
Value
Pg III
Title
Deleted CAS Numbers
Value
174421-33-1; 852222-55-0
Title
CN code
Value
n.a.
Title
CN code
Value
n.a.
Title
C-L inventory
Value
Y
Fermentek Product Category
Food Safety
Food Safety - Sub
Mycotoxins
Food Safety Related
Trichocothecenes
Antibiotics
Cytotoxic agents
Research field: Cancer
Apoptosis related
Signal to sort
A

Quote for

Price
$1.00
15-Acetoxyscirpenol
15-Acetoxyscirpenol animation
15- Acetoxyscirpenol bottle
15-Acetoxyscirpenol
15-Acetoxyscirpenol animation
15- Acetoxyscirpenol bottle
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