Trichostatin A
Molecular Formula
C17H22N2O3
M.W.
302.37
CAS number
58880-19-6
MSDS
Details
Source
Streptomyces platensis
Fermentek product Code
TRA-001
Brand/grade
For research
Specifications
Appearance
White to Off-White powder
Purity by HPLC
≥98% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Melting point
138°C-150°C
Solubility test
Clear colorless solution at 5mg/ml Methanol; Clear yellow solution at 20mg/ml DMSO
Chemical identification
Names and identifiers
Synonyms:
- 2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
- (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
- TSA
- (R)-(+)-Trichostatin A
EU number
611-758-2
Description
Trichostatin A is an antifungal antibiotic.
Trichostatin A is a potent, reversible inhibitor of histone deacetylase (HDAC)
InChl Key
RTKIYFITIVXBLE-QEQCGCAPSA-N
Canonical SMILES
CC(C=C(C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Isomeric SMILES
C[C@H](/C=C(\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
Further Information
Solubility ( literature )
DMSO, Ethanol
Compound Classification
HDAC inhibitor
Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Protect from moisture
Open carefully.
Use the original container to store the product.
Avoid exposing to strong direct light.
Other vendors may recommend higher temperatures for storage.
Retest time
3 Years
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Composition
Ingredient type
Fermentek product
Special Info
Available since
Other Fields
Title
Transport information
Value
Not hazardous for transport
Fermentek Product Category
Signal to sort
T
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