Filipin III
Molecular Formula
C35H58O11
M.W.
654.83
CAS number
480-49-9
Source
Streptomyces filipinensis
Fermentek product Code
FLP-002
Brand/grade
For research
Appearance
White to slight yellow
Purity by HPLC
≥95% ; refer to CoA for more data
Purity By TLC
≥98% ; refer to CoA for more data
Solubility test
Clear colorless solution at 10mg/ml of Methanol
Names and identifiers

Synonyms:

  • Desoxylagosin
  • Filimarisin
  • Filipin

Chemical names:

IUPAC: (17E,19E,21E,23E,25E)-4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethyl-1-oxacyclooctacosa-17,19,21,23,25-pentaen-2-one

RTECS# RN9800000

EU number
637-175-3
Description

Filipin III, a polyene (pentaene) macrocyclic lactone broad spectrum antifungal antibiotic,  also exhibits antitumor and antiviral activities. It acts by binding cell membrane sterols, disrupting membrane integrity.  Filipin III, the most abundant component of  Filipin complex is offered in pure form.

InChl Key
IMQSIXYSKPIGPD-YQRUMEKGSA-N
Canonical SMILES
CCCCCC(C1C(CC(CC(CC(CC(CC(CC(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O
Isomeric SMILES
CCCCCC(C1C(CC(CC(CC(CC(CC(CC(/C(=C/C=C/C=C/C=C/C=C/C(C(OC1=O)C)O)/C)O)O)O)O)O)O)O)O
Compound Classification

 

Warning! This substance causes serious eye irritation, causes skin irritation and may cause respiratory irritation.

 

Storage, handling
Store in a freezer upon arrival, at -10°C to -25°C
Open carefully.
Use the original container to store the product.
Keep the lid tightly closed.
Avoid exposing to strong direct light.
Store under argon.
Other vendors may recommend higher temperatures for storage.
Disclaimer
For Research use only
Not for Human or Drug use
Not extracted from humans or animals
Refer to MSDS for further safety and handling instructions
Warnings
Ingredient type
Fermentek product
Available since
Signal to sort
F