Chelerythrine chloride

Molecular Formula

C21H18NO4∙Cl

M.W.

383.82

CAS number

3895-92-9

Details

Source

Chelidonium majus

Fermentek product Code

CHE-001

Brand/grade

For research

Specifications

Appearance

Yellow powder

Purity by HPLC

≥98% ; refer to CoA for more data

Purity By TLC

≥98% ; refer to CoA for more data

Melting point

202°C-208°C

Solubility test

Clear yellowish solution at 5mg/ml Methanol

Chemical identification

Names and identifiers

EINECS 223-444-9

1,2-Dimethoxy-12-methyl(1,3)benzodioxolo(5,6-c)phenanthridinium chloride

Chelerythrine hydrochloride

EU number

223-444-9

Description

Chelerythrine: A benzophenanthridine alkaloid. A potent, selective, and cell-permeable PKC inhibitor.Chelerythrine is very closely related to sanguinarine. Unlike sanguinarine which is found in the green biomass of Chelidonium, Chelerythrine mainly occurs in its roots.

InChl Key

WEEFNMFMNMASJY-UHFFFAOYSA-M

Canonical SMILES

C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-]

Further Information

Solubility ( literature )

Methanol, Water, DMSO

Compound Classification

Benzophenanthridine alkaloid

PKC inhibitor

Storage, handling

Store in a freezer upon arrival, at -10°C to -25°C